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Table 1 GAD65 autoimmune neurological associations

From: Are anti-glutamic acid decarboxylase 65-kDa isoform antibodies related to diabetes or brain tumor?

Stiff-person syndrome (classic form, limited form, and progressive encephalomyelitis with rigidity and myoclonus)

Cerebellar ataxia

Intractable epilepsy (autoimmune)

Brain stem syndrome

Extrapyramidal syndromes

Corticospinal spasticity

Limbic encephalitis

Peripheral neuropathies

Ocular features (nystagmus and myoclonus features)

Myelopathy

Autonomic neuropathy

Paraneoplastic neurological syndrome includes small-cell or non-small cell lung cancer, other neuroendocrine lineage neoplasms, testicular seminoma, thymoma or thymic carcinomas, thyroid neoplasia, adenocarcinomas of the breast, gastrointestinal tract, and kidney, lymphomas, and myeloma