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Table 3 Bivariate analysis of immunosuppressant medication and underlying diseases between patients regarding their medication interruption status prior or after first SARS-CoV2 immunization

From: Who is pausing immunosuppressive medication for COVID-19 vaccination? Results of an exploratory observational trial

 

Therapy paused (N = 59) n (% proportion)

Therapy continued (N = 148) n (% proportion)

p-value

Underlying diseasea

 Organ transplant

1 (1.7)

13 (8.8)

0.0731

 Inflammatory bowel disease

10 (16.9)

28 (18.9)

0.8441

 Rheumatic disease

35 (59.3)

64 (43.2)

0.0451

 Multiple sclerosis

2 (3.4)

18 (12.2)

0.0681

 Psoriasis

10 (16.9)

20 (13.5)

0.5191

 Other

6 (10.2)

23 (15.5)

0.3801

Immunosuppressantsa

 Conv. immunosuppressants

36 (61.0)

56 (37.8)

0.0031

 Corticoids

23 (39.0)

49 (33.1)

0.4241

 TNF inhibitor

13 (22.0)

26 (17.6)

0.5551

 Other biologicals

12 (20.3)

27 (18.2)

0.6991

 Other

9 (15.3)

42 (28.4)

0.0511

Number of taken immunosuppressants

 1

32 (54.2)

100 (67.6)

0.0722

 2

17 (28.8)

37 (25.0)

 3 or more

10 (16.9)

11 (7.4)

  1. Data are n (%)
  2. aMultiple selection possible
  3. 1Fisher’s exact test
  4. 2Fisher–Freeman–Halton exact test