The role and mechanism of TXNDC5 in diseases

Table 1 TXNDC5 SNP-related diseases

Diseases	SNP	Gene symbol	Location	Ref
Oesophageal cancer	rs1632346 rs9505309 rs2815128 rs2815142	TXNDC5/MUTED MUTED/TXNDC5 MUTED MUTED	INTERGENIC INTERGENIC INTRON MUTED	[21]
Liver cancer	rs13210097 rs11754300 rs9392182 rs2815128	TXNDC5/MUTED TXNDC5/MUTED MUTED/TXNDC5 MUTED	INTERGENIC INTERGENIC INTERGENIC INTRON	[21]
Cervical cancer	rs408014 rs7771314 rs9505298	TXNDC5 TXNDC5 BMP6/TXNDC5	INTRON INTRON COMPLEX	[21, 26]
Hepatocellular carcinoma	rs1225944 rs1225943	TXNDC5 TXNDC5	INTRON INTRON	[27]
Rheumatoid arthritis	rs9505298 rs41302895 rs1225936 rs1225938 rs372578 rs443861 rs408014 rs9392189 rs2743992	BMP6/TXNDC5 TXNDC5/BMP6 TXNDC5 TXNDC5 TXNDC5 TXNDC5 TXNDC5 MUTED MUTED	COMPLEX COMPLEX INTRON INTRON INTRON INTRON INTRON INTRON INTRON	[47]
Nonsegmental vitiligo	rs1043784 rs7764128 rs8643	TXNDC5 TXNDC5 TXNDC5	Exon Exon Exon	[52]
Schizophrenia	rs13873 rs1225934–rs13873	TXNDC5 BMP6–TXNDC5	INTRON -	[53]

ISSN: 2047-783X