The association of nonalcoholic fatty liver disease with bone mineral density in type 2 diabetes

Table 3 Multivariate linear analysis: the effect of the study variables on lumbar spine BMD

	β	P-value	95%Cl (%)	R²
All subjects
T2DM with NAFLD	0.812	< 0.001	0.370–1.253	0.439
T2DM without NAFLD	0.567	0.001	0.220–0.915
Non-diabetes with NAFLD	0.626	0.145	− 0.217–1.470
Age	− 0.024	0.001	− 0.038– − 0.009
Sex (male)	1.574	< 0.001	1.275–1.873
BMI	0.948	< 0.001	0.593–1.304
Subgroup
T2DM				0.401
NAFLD	0.488	0.027	0.010–0.883
BMI	0.085	0.004	0.04–0.155
Age	− 0.03	0.005	− 0.047– − 0.004
Sex (male)	1.366	0.001	1.038–1.956
Non-diabetes
BMI	0.107	0.031	0.040–0.238	0.498
Sex (male)	2.158	0.001	0.845–2.560

All subjects groups, BMI, sex, age, TGs, HDL-C, calcium, UA, ALT, were adjusted. Participants free from diabetes and NAFLD as a reference group
Subgroup: T2DM group, BMI, sex, age, TGs, HDL-C, calcium, UA, ALT, were adjusted
Non-diabetes group, TGs, HDL-C, sex, age, ALT, calcium, UA were adjusted
BMI, body mass index; NAFLD, nonalcoholic fatty liver disease

ISSN: 2047-783X