Table 1 Clinicopathological associations among different groups based on IgG subclass distribution

Male (%)

87.5

61.4

83.3

76.0

Age (year)

56.9 ± 10.0

51.4 ± 9.3

56.0 ± 8.4

55.1 ± 9.1

Duration of diabetes (mo)

102.0 (39.0, 144.0)

96.0 (36.0, 129.0)

60.0 (33.0, 129.0)

120.0 (39.0, 120.0)

Duration of nephropathy (mo)

12.5 (1.0, 42.0)

4.5 (1.0, 21.0)

1.0 (1.0, 1.3)

1.0 (1.0, 6.0)

Proteinuria(g/24 h)

3.2 (1.4, 4.9)

3.2 (1.1, 8.1)

3.4 (1.3, 5.4)

4.2 (1.5, 6.8)

Albumin (g/L)

32.6 ± 5.6

31.6 ± 8.2

29.8 ± 5.0

31.1 ± 6.6

Scr (μmol/L)

145.0 (75.0, 193.0)

95.0 (71.0, 140.0)

123.4 (65.5, 192.9)

118.0 (88.6, 146.5)

eGFR(ml/min/1.73m²)

44.5 (27.5, 117.0)

66.9 (42.0, 114.3)

100.5 (30.9, 106.1)

64.0 (37.0, 94.5)

DN stage I [n(%)]

1 (12.5)

3 (6.8)

1 (16.7)

3 (6.0)

DN stage II [n(%)]

3 (37.5)

7 (15.9)

1 (16.7)

15 (30.0)

DN stage III [n(%)]

3 (37.5)

32 (72.7)

4 (66.7)

31 (62.0)

DN stage IV [n(%)]

1 (12.5)

2 (4.5)

0 (0)

1 (2.0)

IgG intensity

1.0 ± 0.0

1.3 ± 0.6

1.2 ± 0.4

1.2 ± 0.5

C3 intensity

0.0 (0.0, 1.0)

0.0 (0.0, 0.0)

0.0 (0.0, 0.6)

0.0 (0.0, 0.5)

GS (%)

23.2 (11.5, 41.6)

16.7 (7.3, 30.6)

13.4 (4.7, 24.8)

19.8 (11.1, 38.3)

CD34 + area (%)

23.2 ± 8.1

25.3 ± 8.5

25.1 ± 8.1

23.6 ± 8.0

GBM thickness (nm)

715.0 ± 158.3

770.8 ± 174.7

709.2 ± 109.3

734.8 ± 195.3

FPE

2.6 ± 0.5

2.6 ± 0.6

2.8 ± 0.5

2.7 ± 0.7

IFTA score

1.8 ± 0.7

2.0 ± 0.6

2.2 ± 0.8

2.1 ± 0.7

KIM-1 + area (%)

20.0 (15.0, 37.5)

25.0 (10.0, 37.5)

20.0 (17.5, 28.8)

30.0 (20.0, 42.5)

TBM thickness (nm)

1207.3 ± 316.4

1080 ± 287.1

1250 ± 273.1

1345 ± 476.9

Inter-infla score

2.0 (1.0, 2.0)

2.0 (2.0, 2.0)

2.0 (1.5, 3.0)

2.0 (2.0, 2.0)

Hyalinosis score

1.9 ± 0.4

1.8 ± 0.5

1.7 ± 0.7

1.7 ± 0.5

A-sclerosis score

1.0 (0.0, 1.0)

1.0 (0.0, 1.0)

1.0 (0.8, 1.0)

1.0 (0.0, 1.0)