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Table 4 Association of plasma Lp(a) levels with cardiovascular disease in a Mendelian randomization analysis (MR-PRESSO)

From: The relationship between lipoprotein(a) and risk of cardiovascular disease: a Mendelian randomization analysis

 

N

RAW OR

95% CI

Estimates P

outlier N

OR

Corrected 95% CI

Estimates P

AA

11

1.005

1.000–1.009

0.081

NA

NA

NA

NA

CHD

11

1.002

1.001–1.005

0.028

NA

NA

NA

NA

ISL

18

1.003

1.002–1.004

1.40E-06

NA

NA

NA

NA

AF

14

1.001

1.000–1.002

0.081

NA

NA

NA

NA

HBP

16

1.000

0.998–1.002

0.915

NA

NA

NA

NA

HF

12

0.999

0.997–1.002

0.564

NA

NA

NA

NA

IS

16

1.000

1.000–1.001

0.162

NA

NA

NA

NA

LIS

13

1.000

0.999–1.000

0.547

NA

NA

NA

NA

ISS

18

0.999

0.998–1.000

0.445

NA

NA

NA

NA

PE

16

0.999

0.998–1.000

0.228

NA

NA

NA

NA

  1. OR odds ratio, CI confidence interval, AA aortic aneurysm, CHD coronary heart disease, ISL large artery atherosclerosis stroke, AF atrial fibrillation, HBP secondary hypertension HF heart failure, IS ischemic stroke, LIS lacunar stroke. ISS small vessel stroke, PE pulmonary embolism