Fig. 1

Volcano maps, PCA dot plots and hierarchical clustering heat maps of DEGs in TCGA-STAD datasets. X-axis: log2 FC; Y-axis: − log 10 (p-value) for each gene; vertical-dotted lines: | log2 FC |≥ 1.5; horizontal-dotted line: the significance cut off (p-value = 0.05). The red dot represents DEG. Expression heatmap of the top 100 DEGs between 43 cases of early stage STAD (A), 250 cases of advanced stage of STAD (B), and 28 cases of paracancerous normal tissues, respectively