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Fig. 3 | European Journal of Medical Research

Fig. 3

From: The underlying molecular mechanisms and biomarkers of plaque vulnerability based on bioinformatics analysis

Fig. 3

Analysis upstream and downstream TFs of DEGs between unstable carotid plaque and stable plaque. A Transcription factors of all up-regulated mRNAs. B Transcription factors of the all down-regulated mRNAs. C The heatmap of upstream and downstream TFs. TFs regulates the network diagram of mRNA. The red diamond in the center represents the up-regulated TFs–mRNA, the surrounding red ellipses represent the up-regulated mRNA, and the green ellipses represent the down-regulated mRNA D; the green diamond in the center represents the down-regulated TFs–mRNA, the surrounding red ellipses represent the up-regulated mRNA, and the green ellipses represent the down-regulated E, which show top 50 TFs–mRNAs pairs

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