Effects and related mechanism of alpha-adrenergic receptor inhibitor phentolamine in a rabbit model of acute pulmonary embolism combined with shock

Table1 Results of blood gas analysis

Parameter	Time point	S	M	PTL
SaO₂, %	Baseline	96.75 ± 1.67	96.00 ± 2.00	96.50 ± 1.60
	PE	97.00 ± 1.31	67.88 ± 9.39*	68.38 ± 6.63*
	PE-120 min	97.13 ± 1.36	61.25 ± 6.90*	87.63 ± 5.47*†
PaO₂, mmHg	Baseline	93.88 ± 4.52	94.50 ± 5.23	95.75 ± 4.03
	PE	93.75 ± 2.92	37.25 ± 5.90*	40.38 ± 5.71*
	PE-120 min	95.50 ± 6.59	47.50 ± 4.04*	70.14 ± 5.64*†
PaCO₂, mmHg	Baseline	32.38 ± 1.92	33.13 ± 2.23	34.75 ± 3.53
	PE	33.38 ± 1.92	34.50 ± 3.817	34.13 ± 3.56
	PE-120 min	32.00 ± 2.14	35.00 ± 3.56	34.43 ± 3.21

Data are expressed as means ± SD
Baseline before pulmonary embolism, PE pulmonary embolism referring the moment of successful modeling, PE-120 min 120 min after the moment of successful modeling
S sham operation group, M model group, PTL phentolamine group
^*P < 0.05 vs. S group, †P < 0.05, vs. M group

ISSN: 2047-783X