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Table 3 Associations between modified shock index (MSI) and mortality among patients with septic shock before the start of vasopressor therapy

From: Evaluation of SI, MSI and DSI for very early (3-day) mortality in patients with septic shock

 

Quartiles of pre-VPs MSI

P for trend a

Q1

Q2

Q3

Q4

n

316

317

316

317

 

Range

0.44, 1.12

1.12, 1.37

1.37, 1.64

1.64, 5.78

 

3-day mortality

 Crude model

Ref.

1.66 (0.83, 3.47)

2.63 (1.38, 5.28)

3.78 (2.05, 7.45)

 < 0.0001

 Adjusted model 1

Ref.

1.72 (0.85, 3.61)

3.00 (1.56, 6.08)

4.75 (2.53, 9.50)

 < 0.0001

 Adjusted model 2

Ref.

3.22 (1.16, 10.43)

4.46 (1.69, 14.07)

4.29 (1.64, 13.48)

0.01

In-hospital mortality

 Crude model

Ref.

1.09 (0.74, 1.61)

1.61 (1.11, 2.35)

1.5 (1.03, 2.18)

0.01

 Adjusted model 1

Ref.

1.12 (0.75, 1.66)

1.76 (1.21, 2.58)

1.75 (1.19, 2.58)

 < 0.01

 Adjusted model 2

Ref.

1.15 (0.75, 1.78)

1.63 (1.07, 2.48)

1.16 (0.74, 1.81)

0.36

  1. MSI modified shock index, Q quartile, VPs start of vasopressors
  2. a Multiple logistic regression analysis
  3. b Odds ratios (95% confidence interval) (all such values)
  4. Adjusted for age, gender, race, and ICU care unit
  5. Adjusted for variables in model 1 and SOFA score day-1