Table 1 Univariate analysis of factors associated with survival rate
From: Perioperative factors related to the prognosis of elderly patients with hepatocellular carcinoma
Variable | Number | Survival rate (%) | P value* | |||
|---|---|---|---|---|---|---|
1-year | 3-year | 5-year | 10-year | |||
Gender | ||||||
Male | 127 | 76.4 | 57.3 | 41.3 | 19.0 | 0.040 |
Female | 24 | 95.8 | 79.2 | 67.7 | 38.1 | |
Alpha-fetoprotein(ng/ml)a | ||||||
≤ 20 | 39 | 92.3 | 86.2 | 69.9 | 9.7 | 0.000 |
> 20 | 66 | 72.7 | 43.6 | 28.6 | ||
Total bilirubin(μmol/L)a | ||||||
≤ 21 | 93 | 87.1 | 69.7 | 56.5 | 29.6 | 0.001 |
> 21 | 40 | 65.0 | 39.7 | 23.9 | ||
Alkaline phosphatase(U/L)a | ||||||
≤ 130 | 99 | 79.8 | 60.4 | 48.3 | 21.6 | 0.808 |
> 130 | 21 | 50.6 | ||||
HbsAga | ||||||
Negative | 43 | 86.0 | 69.2 | 51.7 | 0.056 | |
Positive | 98 | 75.5 | 55.9 | 41.6 | 18.6 | |
Child–Pugh grade | ||||||
A | 137 | 81.8 | 59.556.3 | 47.625.0 | 23.3 | 0.031 |
B/C | 14 | 71.4 | ||||
Largest tumour size(cm) | ||||||
≤ 5 | 81 | 87.7 | 69.0 | 46.6 | 20.9 | 0.052 |
5 ~ 10 | 48 | 77.1 | 50.3 | 39.622.4 | ||
> 10 | 22 | 63.6 | 40.9 | |||
Number of lesion | ||||||
Single | 111 | 81.1 | 63.8 | 49.3 | 23.9 | 0.441 |
Multiple | 40 | 75.0 | 49.2 | 35.4 | 17.5 | |
Differentiationa | ||||||
Well differentiated | 24 | 91.7 | 74.5 | 69.546.7 | 51.511.8 | 0.000 |
Moderately differentiated | 64 | 82.8 | 66.8 | 17.5 | ||
Poorly differentiated | 33 | 54.5 | 30.0 | |||
Previous abdominal surgery | ||||||
No | 125 | 81.6 | 56.6 | 43.8 | 19.6 | 0.013 |
Yes | 26 | 80.8 | 76.0 | 60.7 | ||
≥ 3 segments resected | ||||||
No | 111 | 81.1 | 63.8 | 49.3 | 23.9 | 0.441 |
Yes | 40 | 75.0 | 52.5 | 39.4 | 17.5 | |
Resection style | ||||||
No anatomical | 117 | 85.5 | 65.6 | 51.3 | 28.8 | 0.008 |
Anatomical | 34 | 67.6 | 44.1 | 29.8 | 14.9 | |
Operating time(min) | ||||||
≤ 180 | 100 | 88.0 | 62.9 | 52.0 | 31.1 | 0.064 |
> 180 | 51 | 76.5 | 43.5 | 35.3 | 15.3 | |
Intraoperative blood loss(ml) | ||||||
≤ 400 | 114 | 89.5 | 63.8 | 51.0 | 32.8 | 0.006 |
> 400 | 37 | 67.6 | 51.4 | 30.8 | 5.5 | |
Intraoperative blood transfusion | ||||||
No | 101 | 87.1 | 64.1 | 50.0 | 33.0 | 0.065 |
Yes | 50 | 68.0 | 54.0 | 39.6 | 17.7 | |
Complication | ||||||
No | 132 | 81.1 | 61.2 | 47.4 | 27.3 | 0.739 |
Yes | 19 | 68.4 | 39.4 | 19.7 | ||