Table 2 Top 10 significant drugs targeting the genes in green module
From: Identification of significant modules and hub genes involved in hepatic encephalopathy using WGCNA
Term | p-value | q-value | overlap_genes |
|---|---|---|---|
VITAMIN E CTD 00006994 | 0.000006 | 0.003297 | [ITPKB, TUBA1C, PON2, TRIP6, MSN, STOM, PBXIP1, F3, FOXO1] |
anisomycin HL60 DOWN | 0.000041 | 0.011218 | [ITPKB, PON2, MSN, CYBRD1, STOM, PBXIP1, METTL7A] |
quercetin HL60 DOWN | 0.000259 | 0.028065 | [PON2, METTL7A] |
wortmannin CTD 00000504 | 0.000397 | 0.028065 | [YAP1, F3, FOXO1] |
rifabutin PC3 UP | 0.000438 | 0.028065 | [PLSCR4, STOM, FOXO1] |
VALPROIC ACID CTD 00006977 | 0.000529 | 0.028065 | [YAP1, HDDC2, PON2, SLC1A3, CYBRD1, PAX6, PBXIP1, F3, FOXO1, ITPKB, RAB34, PLSCR4, TRIP6, STOM, METTL7A, PLTP] |
Medroxyprogesterone acetate CTD 00006623 | 0.000533 | 0.028065 | [SLC1A3, STOM, F3, FOXO1] |
sodium benzoate BOSS | 0.000620 | 0.028065 | [PON2, F3] |
2,6-Di-tert-butyl-4-methylphenol CTD 00005548 | 0.000724 | 0.028065 | [PON2, F3] |
MS-275 PC3 UP | 0.000783 | 0.028065 | [PLSCR4, STOM, F3, FOXO1] |