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Table 2 Clinical biochemical indexes and pulmonary infection-related AKI

From: The ratio of monocytes to lymphocytes multiplying platelet predicts incidence of pulmonary infection-related acute kidney injury

Variables

AKI (n = 177)

non-AKI (n = 764)

Total (n = 941)

AKI

Severe AKI

aOR (95% CI)

P

aOR (95% CI)

P

Renal function

 BUN (mmol/L)

9.78 ± 6.40

5.85 ± 3.11

6.59 ± 4.23

1.23 (1.17–1.29)

 < 0.001

1.20 (1.14–1.28)

 < 0.001

 SCr (µmol/L)

111.55 ± 62.95

72.82 ± 29.35

80.11 ± 40.87

1.02 (1.02–1.03)

 < 0.001

1.02 (1.01–1.02)

 < 0.001

 eGFR (ml/min/1.73m2)

64.14 ± 27.79

90.11 ± 23.89

85.23 ± 26.67

0.96 (0.96–0.97)

 < 0.001

0.97 (0.96–0.98)

 < 0.001

 Uric acid (µmol/L)a

362.29 ± 165.90

266.96 ± 117.80

284.89 ± 133.44

1.05 (1.04–1.06)

 < 0.001

1.04 (1.02–1.06)

 < 0.001

Liver function

 AST (IU/L)a

26 [17–43]

23 [16–33]

23 [16–34]

1.05 (1.02–1.08)

 < 0.001

1.05 (1.02–1.08)

0.005

 ALT (IU/L)a

19 [12–37]

21 [13–36]

21 [13–36]

1.02 (1.00–1.05)

0.194

1.02 (1.00–1.05)

0.146

 Total bilirubin (µmol/L)

14.93 ± 15.47

11.94 ± 13.59

12.51 ± 14.00

1.02 (1.00–1.03)

0.006

1.02(1.00–1.03)

0.006

Other laboratory indexes

 Hemoglobin (g/L)a

111.45 ± 25.51

116.68 ± 23.26

115.70 ± 23.38

0.89 (0.82–0.96)

0.003

0.91 (0.82–1.01)

0.074

 Hematocrit (L/L)

33.61 ± 7.19

35.10 ± 6.68

34.82 ± 6.80

0.96 (0.94–0.99)

0.003

0.97 (0.93–1.00)

0.050

 Platelet (109/L)a

137.36 ± 88.07

208.55 ± 101.54

195.16 ± 102.94

0.92 (0.90–0.94)

 < 0.001

0.85 (0.82–0.89)

 < 0.001

 Total protein (g/L)

63.12 ± 8.36

64.79 ± 8.82

64.47 ± 8.76

0.98 (0.96–1.00)

0.060

0.99 (0.96–1.02)

0.374

 Albumin (g/L)

34.65 ± 5.37

36.01 ± 6.28

35.76 ± 6.14

0.96 (0.94–0.99)

0.020

0.96 (0.92–1.00)

0.050

 Globulin (g/L)

28.44 ± 7.21

28.78 ± 6.45

28.72 ± 6.60

1.00 (0.97–1.03)

0.949

1.01 (0.97–1.04)

0.599

 Albumin and globulin ratio

1.29 ± 0.36

1.31 ± 0.37

1.31 ± 0.37

0.79 (0.49–1.28)

0.345

0.77 (0.39–1.46)

0.427

 CRP (mg/L)

46.3 [15.6–125.5]

36.9 [10.3–94.1]

38.3 [11.2–96.6]

1.00 (1.00–1.00)

0.271

1.00 (1.00–1.01)

0.017

 PCT (ng/mL)

0.40 [0.15–1.17]

0.10[0.05–0.32]

0.13 [0.06–0.44]

1.41 (1.23–1.63)

 < 0.001

1.50 (1.27–1.75)

 < 0.001

Electrolyte

 Sodium (mmol/L)a

139.67 ± 6.05

138.89 ± 4.54

139.04 ± 4.87

1.22 (0.87–1.72)

0.241

0.94 (0.58–1.52)

0.789

 Potassium (mmol/L)

4.02 ± 0.57

3.91 ± 0.59

3.93 ± 0.59

1.41 (1.04–1.95)

0.031

1.31 (0.87–2.01)

0.215

 Chlorine (mmol/L)a

102.68 ± 6.51

101.39 ± 4.98

101.64 ± 5.32

1.45 (1.06–2.00)

0.020

1.21 (0.77–1.90)

0.416

 Calcium (mmol/L)

2.14 ± 0.20

2.16 ± 0.17

2.16 ± 0.18

0.57 (0.19–1.72)

0.321

0.86 (0.20–3.59)

0.834

 Phosphorus (mmol/L)

1.01 ± 0.34

1.00 ± 0.27

1.01 ± 0.28

1.92 (0.92–3.99)

0.082

1.17 (0.45–3.07)

0.750

 Magnesium (mmol/L)

0.85 ± 0.12

0.86 ± 0.10

0.85 ± 0.10

0.47 (0.07–3.03)

0.427

0.17 (0.01–1.99)

0.159

 CO2 (mmol/L)

25.26 ± 4.07

26.08 ± 3.52

25.92 ± 3.65

0.91 (0.87–0.96)

 < 0.001

0.89 (0.84–0.95)

 < 0.001

Arterial blood gas analysis

 pH

7.42 ± 0.09

7.44 ± 0.32

7.43 ± 0.29

1.00 (0.94–1.09)

0.926

1.01 (0.95–1.13)

0.846

 PCO2 (kPa)

40.40 ± 13.27

39.41 ± 9.38

39.60 ± 10.24

1.00 (0.98–1.02)

0.771

0.98 (0.95–1.01)

0.209

 PO2 (kPa)

92.16 ± 45.84

85.23 ± 32.56

86.55 ± 35.53

1.01 (1.00–1.01)

0.051

1.01 (1.00–1.01)

0.050

 HCO3− (mmol/L)

25.51 ± 6.29

27.15 ± 4.89

26.83 ± 5.23

0.93 (0.89–0.97)

 < 0.001

0.91 (0.86–0.96)

0.002

 Base excess (mmol/L)

0.3 [-2.8–4.3]

2.6 [0.3–5.2]

2.5 [0.0–5.2]

0.91 (0.87–0.94)

 < 0.001

0.86 (0.81–0.92)

 < 0.001

  1. AKI acute kidney injury, BUN blood urea nitrogen, SCr serum creatinine, eGFR estimated glomerular filtration rate, AST aspartate transaminase, ALT alanine transaminase, CO2 Carbon dioxide, PCO2 carbon dioxide partial pressure, PO2: oxygen partial pressure, HCO3− bicarbonate ion aOR was adjusted by age, gender, and body mass index, CRP C-reactive protein, PCT procalcitonin
  2. aOR increased by 10 units
  3. bOR increased by 0.1 units
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European Journal of Medical Research

ISSN: 2047-783X

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