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Table 2 Univariate and multivariate analysis of risk factors for MVI of HCC

From: Identification of DNA methylation signatures for hepatocellular carcinoma detection and microvascular invasion prediction

Risk factor

Univariate analysis

 

Multivariate analysis

Odds ratio

P-value

 

Odds ratio

P-value

Age (years)

0.97 (0.92, 1.04)

0.418

   

Gender

0.31 (0.03, 3.34)

0.336

   

HBsAg

2.27 (0.19, 27.58)

0.521

   

AFP (≥ 400 ng/mL)

7.11 (1.23, 40.98)

0.028*

 

3.10 (0.26, 36.86)

0.370

Tumor size (cm)

1.2 (0.29, 5.02)

0.803

   

BCLC stage

1.46 (0.32, 6.70)

0.628

   

TNM stage

0.58 (0.09, 4.01)

0.584

   

DNA methylation signature

60.00 (7.48, 481.57)

 < 0.001*

 

47.51 (5.74, 393.27)

 < 0.001*

  1. *Data are statistically significant results from logistic regression analysis
  2. AFP alpha-fetoprotein, HBsAg hepatitis B surface antigen
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European Journal of Medical Research

ISSN: 2047-783X

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