Table 1 Patients and treatment characteristics

Baseline characteristics

 Age (years)

62 [50.5–73]

56 [41.25–71.75]

0.078

 Male

32 (56.1)

71 (50.7)

0.489

 Presence of risk factors for DRSP

52 (91.2)

104 (74.3)

0.008

 Number of risk factors for DRSP

3 [2, 3]

2 [0–3]

0.045

Risk factors for DRSP

0.071

 Comorbidity^a

52 (91.23)

92 (65.71)

 Diabetes mellites

38 (66.67)

65 (46.43)

 Immunosuppression

0 (0)

13 (9.29)

 Received antibiotic therapy within 3 months

3 (5.26)

4 (2.86)

 Age ≥ 65 years

25 (43.86)

42 (30)

 MRSA or Pseudomonas infection in the past year

1 (1.8)

1 (0.7)

0.509

 Hospitalization or IV antibiotics within 3 months

6 (10.5)

12 (8.6)

0.666

 Respiratory culture ordered

13 (22.8)

47 (33.6)

0.137

 Chest infiltration

44 (78.6)

95 (73.6)

0.476

 Baseline SpO₂ (%)

93 [90.5–96]

94 [87–97]

0.745

 Presence of Leukocytosis

23 (40.4)

83 (59.3)

0.016

 Presence of fever

24 (42.1)

39 (27.9)

0.052

 Baseline C-reactive protein, mg/L^b

21.05 [7.1–63.7]

48.1 [20.5–136.5]

0.024

Treatment Characteristics

Primary β-Lactam

0.284

 Ceftriaxone

57 (100)

134 (95.7)

 Cefuroxime

0 (0)

4 (2.9)

 Amoxicillin

0 (0)

2 (1.4)

Switched to another β-Lactam^c

0.299

 Cefuroxime

6 (85.7)

24 (57.1)

 Amoxicillin

0 (0)

14 (33.3)

 Cefazolin

0 (0)

1 (2.4)

 Ceftazidime

1 (14.3)

3 (7.1)

 Changed β-Lactam for discharge

7 (12.3)

42 (30)

0.009

 DOT (days)

9 [7–13.5]

7 [6–10]

0.003