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Table 3 Subgroup analysis of patients who received macrolides

From: Doxycycline vs. macrolides in combination with a β-lactam antibiotic for the treatment of community-acquired pneumonia in inpatients

Outcome

BL-AZM (n = 74)

BL-CLR (n = 66)

P value

Time to clinical stability (days)

5 [3–7]

3 [1–4.75]

 < 0.0001

Clinical cure

72 (97.3)

56 (84.8)

0.01

LOS (days)

6.5 [5–9.25]

8 [6–10.25]

0.02

ICU admission

0 (0)

3 (4.5)

0.06

In-hospital mortality

0 (0)

2 (3%)

0.13

30 day readmission

7 (9.5)

6 (9.1)

0.94

Elevation of liver enzymes

22 (29.7)

8 (12.1)

0.01

  1. Results are presented as n (%) or median [IQR]
  2. BL-AZM β-Lactam + azithromycin, BL-CLR β-Lactam + clarithromycin, ICU intensive care unit, IQR interquartile range, LOS length of stay