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Table 1 Basic characteristics of all participants

From: PD-1 and LAG-3-positive T cells are associated with clinical outcomes of relapsed/refractory multiple myeloma patients

Variables

RRMM (n = 71)

MM (n = 70)

Healthy (n = 70)

p1

p2

Age (year)

63 (48–76)

64.5 (49–76)

61.5 (48–75)

0.554

0.292

Sex (male, %)

48 (67.61)

43 (61.43)

45 (64.29)

0.361

0.620

BMI (kg/m2)

21.87 ± 3.70

22.32 ± 3.29

21.98 ± 3.42

0.436

0.847

ISS stage (n, %)

0.750

 

 I

14 (19.72)

16 (22.86)

  

 II

24 (33.80)

25 (35.71)

  

 III

33 (46.48)

29 (41.43)

  

Disease course (mon)

7 (5–9)

  

Ig type (n, %)

0.511

 

 IgG

41 (57.75)

34 (48.57)

  

 IgA

11 (15.49)

16 (22.86)

  

 IgM

0 (0)

0 (0)

  

 Light chain λ

10 (14.08)

10 (14.29)

   

 Light chain κ

9 (12.68)

10 (14.29)

  

Mediations used before (n, %)

 Lenalidomide

35 (49.30)

  

 Dexamethasone

59 (83.10)

  

 Bortezomib

40 (56.34)

  

 Adriamycin

12 (16.90)

  

 1-year mortality (n, %)

12 (16.90)

4 (5.71)

0.012

  1. p1 comparison between MM and RRMM patients; p2 comparison between RRMM and healthy control
  2. Normally and non-normally distributed data were expressed as mean ± SD or median (range), respectively. Comparison between two groups was conducted by Student’s t test and Mann–Whitney U test for normally and non-normally distributed data, respectively