Table 2 Baseline characteristics of training and validation sets
From: Early predicting 30-day mortality in sepsis in MIMIC-III by an artificial neural networks model
Variables | Training set (n = 1698) | Validation set (n = 1176) | P value |
|---|---|---|---|
Age (IQR, year) | 66 (56–80) | 67 (56–79) | 0.213 |
Gender (n, %) | 0.994 | ||
Male | 939 (55.3%) | 663 (56.3%) | |
Female | 759 (44.7%) | 513 (43.7%) | |
Vital signs | |||
DBP (mmHg) | 63 (51–73) | 63 (51–72) | 0.310 |
SBP (mmHg) | 114 (98–131) | 115 (97–131) | 0.763 |
HR (beats/min) | 97 (81–111) | 97 (83–113) | 0.122 |
RR (beats/min) | 21 (16–24) | 20 (16–24) | 0.148 |
Comorbidities | |||
Renal disease (n, %) | 149 (8.8%) | 92 (7.8%) | 0.930 |
CAD (n, %) | 260 (15.3%) | 197 (16.7%) | 0.542 |
Diabetes (n, %) | 103 (6.1%) | 52 (4.4%) | 0.021 |
Hypertension (n, %) | 636 (37.5%) | 453 (38.5%) | 0.774 |
Laboratory characteristics | |||
PLT (*109/L) | 237.0 (137.0–310.0) | 245.0 (148.0–320.0) | 0.894 |
AST (IU/L) | 193.0 (24.0–83.0) | 174.0 (22.0–73.0) | 0.303 |
Sodium (mmol/L) | 137.0 (134.0–141.0) | 137.0 (134.0–141.0) | 0.931 |
Glucose (mg/dL) | 151.0 (101.7–163.0) | 155.0 (104.7–164.2) | 0.194 |
Chloride (mmol/L) | 102.0 (98.0–107.0) | 101.0 (97.0–106.0) | 0.510 |
MCV (fL) | 91.0 (86.0–96.0) | 90.0 (86.0–95.0) | 0.096 |
ALT (IU/L) | 107.0 (17.0–59.0) | 98.0 (16.0–57.0) | 0.420 |
Neutrophils (%) | 78.0 (74.1–89.1) | 77.0 (73.0–89.0) | 0.144 |
Urea Nitrogen (mg/dL) | 36.0(17.0–46.0) | 35.0 (18.0–46.0) | 0.617 |
PTT (s) | 35.0 (27.2–38.0) | 34.0 (26.9–37.1) | 0.886 |
Hematocrit (%) | 33.0 (28.8–37.5) | 34.0 (29.6–38.1) | 0.355 |
PT(s) | 18.0 (13.3–19.1) | 18.0 (13.2–18.4) | 0.949 |
Anion Gap (mmol/L) | 16.0 (14.0–19.0) | 16.0 (13.0–19.0) | 0.070 |
RDW (%) | 15.0 (14.1–17.1) | 15.0 (14.1–16.9) | 0.612 |
Lymphocytes (%) | 11.0 (4.3–13.3) | 11.0 (4.2–14.0) | 0.063 |
WBC (*109/L) | 13.0 (7.7–17.5) | 12.0 (7.5–16.5) | 0.089 |
NLR | 15.0 (5.5–18.9) | 15.0 (5.4–19.2) | 0.088 |
Total calcium (mg/dL) | 8.0 (7.5–8.8) | 8.0 (7.4–8.8) | 0.381 |
Lactate (mmol/L) | 2.0 (1.4–3.2) | 2.0 (1.4–3.4) | 0.790 |
Albumin (g/dL) | 2.0 (2.5–3.4) | 2.0 (2.4–3.4) | 0.169 |
Creatinine (mg/dL) | 1.0 (0.9–2.2) | 1.0 (0.9–2.4) | 0.893 |
Total bilirubin (mg/dL) | 2.0 (0.4–1.5) | 1.0 (0.4–1.5) | 0.743 |
Scoring system | |||
APACHEII (IQR) | 13 (11–17) | 14 (11–17) | 0.581 |
SOFA (IQR) | 2(1–4) | 2 (1–4) | 0.671 |
Clinical outcomes | |||
LOS in hospital (days) | 13 (5–17) | 13 (5–18) | 0.386 |
30-day mortality (n, %) | 526 (30.9%) | 330 (28.1%) | 0.153 |