Table 3 Comparison of variables between survivor and nonsurvivor groups in training set
From: Early predicting 30-day mortality in sepsis in MIMIC-III by an artificial neural networks model
Variables | Survivor (n = 1172) | Non-survivor (n = 526) | P value |
|---|---|---|---|
Age (IQR, year) | 65 (54–77) | 70 (60–83) | < 0.001 |
Gender | 0.539 | ||
Male (n, %) | 645 (55.8%) | 294 (55.9%) | |
Female (n, %) | 527 (44.2%) | 232 (44.1%) | |
Vital signs | |||
DBP (mmHg) | 63 (52–73) | 62 (49–72) | 0.348 |
SBP (mmHg) | 115 (98–130) | 113 (97–131) | 0.185 |
HR (beats/min) | 96 (81–110) | 98 (82–112) | 0.187 |
RR (beats/min) | 20 (16–24) | 21 (17–25) | 0.223 |
Comorbidities | |||
Renal diseases (n, %) | 96 (8.02%) | 53 (10.64%) | 0.117 |
CAD (n, %) | 172 (14.68%) | 88 (16.73%) | 0.287 |
Diabetes (n, %) | 74 (6.31%) | 29 (5.51%) | 0.728 |
Hypertension (n, %) | 441 (37.62%) | 195 (37.07%) | 0.637 |
laboratory characteristics | |||
PLT (*109/L) | 234.0 (151.0–313.0) | 230.0 (122.7–302.0) | 0.121 |
AST (IU/L) | 109.0 (23.0–70.0) | 374.0 (27.0–128.5) | < 0.001 |
Sodium (mmol/L) | 137.0 (134.0–140.0) | 137.0 (133.0–141.0) | 0.757 |
Glucose (mg/dL) | 154.0 (103.0–163.0) | 146.0 (99.0–165.0) | 0.164 |
Chloride (mmol/L) | 102.0 (98.0–107.0) | 102.0 (97.0–107.0) | 0.751 |
MCV (fL) | 90.0 (86.0–95.0) | 92.0 (88.0–98.0) | 0.001 |
ALT (IU/L) | 73.0 (16.0–55.0) | 180.0 (17.0–74.5) | < 0.001 |
Neutrophils (%) | 79.0 (74.4–89.0) | 77.0 (73.7–89.5) | 0.125 |
Urea Nitrogen (mg/dL) | 32.0 (16.0–40.0) | 44.0 (22.0–57.0) | < 0.001 |
PTT (s) | 34.0 (26.7–35.7) | 38.0 (28.4–41.5) | < 0.001 |
Hematocrit (%) | 33.0 (29.0–37.6) | 33.0 (28.4–37.0) | 0.248 |
PT (s) | 17.0 (13.2–17.5) | 20.0 (13.9–22.0) | < 0.001 |
Anion Gap (mmol/L) | 16.0 (13.0–19.0) | 16.0 (14.0–20.0) | 0.267 |
RDW (%) | 15.0 (13.9–16.6) | 16.0 (14.7–18.3) | < 0.001 |
Lymphocytes (%) | 10.0 (4.4–13.3) | 11.0 (4.0–13.3) | 0.499 |
WBC (*109/L) | 13.0 (7.8–17.0) | 13.0 (7.3–18.6) | 0.083 |
NLR | 15.0 (5.6–18.8) | 15.0 (5.2–18.8) | 0.875 |
Total calcium (mg/dL) | 8.0 (7.6–8.8) | 8.0 (7.5–8.8) | 0.196 |
Lactate (mmol/L) | 2.0 (1.3–2.9) | 3.0 (1.7–3.9) | < 0.001 |
Albumin (g/dL) | 3.0 (2.5–3.4) | 2.0 (2.3–3.1) | < 0.001 |
Creatinine (mg/dL) | 1.0 (0.9–2.0) | 1.0 (0.9–2.2) | 0.238 |
Total bilirubin (mg/dL) | 1.0 (0.4–1.2) | 3.0 (0.4–2.6) | < 0.001 |
Scoring system | |||
APACHEII (IQR) | 13 (10–16) | 15 (12–18) | < 0.001 |
SOFA (IQR) | 2 (1–4) | 3 (2–5) | < 0.001 |
Clinical outcomes | |||
LOS in hospital (days) | 16 (6–20) | 8 (3–13) | < 0.001 |