Table 1 The basic characteristics of the included studies
First author | Year | Region | Study design | Number of patients | Agea | Gender (M:F) | NOS | |||
|---|---|---|---|---|---|---|---|---|---|---|
Simultaneous resection | Staged resection | Simultaneous resection | Staged resection | Simultaneous resection | Staged resection | |||||
Valdimarsson | 2020 | Sweden | nRCT | 160 | 377 | 65 (58–72) | 66 (58–73) | (90:70) | (234:143) | 6 |
Kaibori | 2010 | Japan | nRCT | 32 | 42 | 62.3 ± 9.3 | 65.0 ± 9.9 | (17:15) | (27:15) | 7 |
Le Souder | 2018 | Canada | nRCT | 26 | 27 | 54.7 ± 12.9 | 58.7 ± 9.2 | (14:12) | (12:15) | 7 |
Luo | 2010 | China | nRCT | 129 | 276 | 58 (42–69) | 60 (43–70) | (76:53) | (156:120) | 6 |
Martin | 2009 | USA | nRCT | 70 | 160 | 58 | 61 | (54:46) | (57:43) | 6 |
Martin | 2003 | USA | nRCT | 134 | 106 | 64 (27–85) | 61 (23–82) | (69:65) | (61:45) | 7 |
Moug | 2010 | United Kingdom | nRCT | 32 | 32 | 69 (53–79) | 67 (37–82) | (18:14) | (21:11) | 6 |
She | 2014 | China | nRCT | 28 | 88 | 65.5 (29–75) | 59 (24–81) | (22:6) | (59:29) | 8 |
Thelen | 2007 | Germany | nRCT | 40 | 179 | 60.5 ± 13.4 | 59.7 ± 10.7 | (24:16) | (96:84) | 8 |
Tsilimigras | 2021 | USA, Italy, Romania | nRCT | 314 | 379 | 61 (51–69) | 59 (51–66) | (189:125) | (224:152) | 6 |
Turrini | 2007 | France | nRCT | 57 | 62 | 60 | 59 | (48:9) | (51:11) | 7 |
Weber | 2003 | France | nRCT | 35 | 62 | 58 ± 12 | 60 ± 9 | (18:17) | (31:31) | 7 |
Yan | 2007 | Australia | nRCT | 73 | 30 | 60 ± 10 | 59 ± 13 | (33:40) | (15:15) | 7 |
Vassiliou | 2007 | Greece | nRCT | 25 | 78 | 63 ± 12 | 61 ± 14 | (15:10) | (47:31) | 6 |
de Haas | 2010 | France | nRCT | 26 | 26 | 60 ± 8 | 60 ± 8 | (17:9) | (17:9) | 7 |
Boudjema | 2020 | France | RCT | 39 | 46 | 68 ± 9 | 66 ± 11 | (25:14) | (25:21) | / |
Kye | 2019 | Korea | nRCT | 143 | 65 |  ≤ 65(93:51) |  > 65(50:14) | (102:41) | (43:22) | 7 |
Abbott | 2012 | USA | nRCT | 60 | 84 | 57.5 (45.5–63.9) | 53.3 (45.5–60.8) | (40:20) | (49:35) | 8 |
Capussotti | 2006 | Italy | nRCT | 31 | 48 | 62.4 (49–78) | 59.3 (31–77) | (18:13) | (27:21) | 7 |
Chua | 2004 | USA | nRCT | 64 | 32 | 63 ± 11 | 61 ± 12 | (39:25) | (18:14) | 6 |
Wu | 2022 | China | nRCT | 495 | 495 | 57.2 ± 11.4 | 57.3 ± 11.2 | (296:199) | (293:202) | 6 |
Thongkan | 2020 | Thailand | nRCT | 21 | 90 | 56.4 ± 12.6 | 61.3 ± 11.5 | (13:8) | (47:43) | 7 |
Karam | 2022 | France | nRCT | 22 | 22 | 65 (60–77) | 59 (52–65) | (20:2) | (14:8) | 7 |