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Table 1 Accuracy, sensitivity, and specificity of preoperative endoscopic diagnosis for differentiation between C3 and C4/5 lesions

From: Current endoscopic diagnosis treatment strategy for superficial nonampullary duodenal tumours

Diagnostic techniques

Endoscopic diagnostic criteria

Cases

Accuracy (%)

Sensitivity (%)

Specificity (%)

Refs.

White light endoscopy

A scoring system based on lesion diameter, color, macroscopic type, and nodularity

134

86

88

79

[6]

ME-CV

A diagnostic algorithm based on magnifying mucin phenotypes including four patterns, convoluted, leaf-like, reticular/sulciolar, and colon-like pattern

76

78.9

63.6

85.2

[7]

ME-NBI

Mucosal and vascular patterns including network, disappeared, white opaque substance and intrastructural vessels

156

72

63

76

[35]

Endocytoscopy

An endocytoscopic classification based on the structural atypia, nuclear morphology and size

93

86.7

87.7

85.4

[11]

  1. The superficial nonampullary duodenal epithelial tumors were classified into three categories: C3 corresponds to low-grade adenoma; C4 included both high-grade adenoma and non-invasive carcinoma; C5 corresponds to invasive carcinoma
  2. ME-CV, magnifying endoscopy with crystal violet staining; ME-NBI, magnifying endoscopy with narrow-band imaging