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Table 2 Comparative efficacy of AFB smear, Xpert, culture, and TB-DNA

From: The value of Xpert MTB/RIF assay of urine samples in the early diagnosis of smear-negative urinary tuberculosis

Test

Sensitivity (CI)

Specificity (CI)

FPV(CI)

FNV(CI)

AFB

77.8% (7/9)*

33.6% (37/110)*

5.1% (2/39)*

33.6% (37/110)

(0.128–2.691)

(0.941–1.149)

(0.083–0.323)

(7.986–12.451)

Xpert

78.9% (15/19)

68.6% (24/35)

14.3% (4/28)

42.3% (11/26)

(0.094–0.650)

(1.262–3.253)

(0.232–0.684)

(1.325–8.005)

Culture

75.0% (3/4)*

27.6% (8/29)*

11.1% (1/9)*

87.5% (21/24)

(0.106–7.477)

(0.771–1.339)

(0.525–1.775)

(0.183–6.665)

TB-DNA

83.3% (5/6)

38.5% (10/26)*

9.1% (1/11)*

76.2% (16/21)

(0.051–2.876)

(0.881–1.616)

(0.462–1.181)

(0.361–14.737)

  1. Sensitivity, specificity, false positivity, and false negativity values of AFB, Xpert, culture, and TB-DNA in the detection of urine samples from UTB participants
  2. AFB Acid-Fast Bacilli smears Xpert Xpert MTB/RIF assay culture culture for MTB TB-DNA Mycobacterium tuberculosis deoxyribonucleic acid CI confidence interval FPV false positivity value FNV false negativity value
  3. *P < 0.05