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Table 4 Efficacy results for Xpert, MGIT 960 culture, and TB-DNA compared to AFB-negative results

From: The value of Xpert MTB/RIF assay of urine samples in the early diagnosis of smear-negative urinary tuberculosis

Test

Sensitivity (CI)

Specificity (CI)

FPV(CI)

FNV(CI)

Xpert

75% (6/8)

53.6% (15/28)

11.8% (2/17)

68.4% (13/28)

(0.086–1.605)

(0.908–1.832)

(0.352–1.088)

(0.615–7.470)

culture

100% (1/1)

25% (5/20)**

0% (0/5)***

75% (15/20)

–

(0.940–1.211)

–

(0.582–0.966)

TB-DNA

100% (4/4)

38.9% (7/18)*

0% (0/7)***

61.1% (11/18)

–

(1.005–1.850)

–

(0.432–0.883)

  1. Sensitivity, specificity, false positivity, and false negativity values of AFB, Xpert, culture, and TB-DNA in the detection of smear-negative urine samples from UTB participants
  2. Xpert Xpert MTB/RIF assay culture culture for MTB TB-DNA Mycobacterium tuberculosis deoxyribonucleic acid CI confidence interval FPV false positivity value FNV false negativity value
  3. *P < 0.05
  4. **P < 0.01
  5. ***P < 0.001