The associations of total testosterone with probable nonalcoholic steatohepatitis and nonalcoholic fatty liver disease fibrotic progression in men with type 2 diabetes: a cross-sectional study

Table 2 The association of testosterone with inflammatory progression of NAFLD

	Total testosterone^a				P for trend	1 SD increment for ln (TT)
	Quartile 1	Quartile 2	Quartile 3	Quartile 4	P for trend	1 SD increment for ln (TT)
Men
Simple NAFLD	2.73 (1.70–4.39)*	1.95 (1.27–3.00)*	1.54 (1.03–2.30)*	Ref.	<0.001	0.73 (0.62–0.86)*
Probable NASH	2.07 (1.31–3.28)*	1.22 (0.78–1.90)	1.05 (0.68–1.61)	Ref.	0.002	0.76 (0.64–0.91)*
Inflammatory of progression of NAFLD	1.83 (1.31–2.54)*	1.36 (0.99–1.87)	1.13 (0.84–1.54)	Ref.	<0.001	0.81 (0.72–0.92)*

Data are shown as regression coefficients or odds ratios (95% CI). Multinomial and ordinal logistic regression analyses were used
^aQuartiles of total testosterone, nmol/L: men: ≤10.75, 10.76–14.06, 14.07–17.88, ≥17.89. Inflammatory progression of NAFLD, ranging from non-NAFLD to simple NAFLD and probable NASH; NAFLD, nonalcoholic fatty liver disease; NASH, nonalcoholic steatohepatitis. The model was adjusted for age, duration of diabetes, current smoking, waist circumference, dyslipidemia, and hypertension. *P < 0.05

ISSN: 2047-783X