The associations of total testosterone with probable nonalcoholic steatohepatitis and nonalcoholic fatty liver disease fibrotic progression in men with type 2 diabetes: a cross-sectional study

Table 3 The association of testosterone with fibrotic progression of NAFLD

	Total testosterone^a				P for trend	1 SD increment for ln (TT)
	Quartile 1	Quartile 2	Quartile 3	Quartile 4	P for trend	1 SD increment for ln (TT)
Men
Indeterminate group	1.02 (0.46–2.29)	1.23 (0.56–2.75)	0.81 (0.37–1.79)	Ref.	0.697	0.95 (0.68–1.32)
Presence of significant fibrosis	0.35 (0.14–0.90)*	0.65 (0.26–1.67)	0.58 (0.23–1.45)	Ref.	0.044	1.27 (0.87–1.85)
Fibrotic progression of NAFLD	0.45 (0.29–0.72)*	0.66 (0.42–1.05)	0.70 (0.44–1.11)	Ref.	0.001	1.24 (1.07–1.45)*

Data are shown as regression coefficients or odds ratios (95% CI). Multinomial and ordinal logistic regression analyses were used
^aQuartiles of total testosterone, nmol/L: men: ≤10.75, 10.76–14.06, 14.07–17.88, ≥17.89. Fibrotic progression of NAFLD, ranging from absence of significant fibrosis to indeterminate group and presence of significant fibrosis; NAFLD, nonalcoholic fatty liver disease. The model was adjusted for age, duration of diabetes, current smoking, waist circumference, dyslipidemia, and hypertension. *P < 0.05

ISSN: 2047-783X