Table 1 Baseline information of original cohort and propensity scored matching cohort
Non-CVP (n = 5528) | CVP (n = 1861) | P value | Non-CVP (n = 1241) | CVP (n = 1241) | P value | |
|---|---|---|---|---|---|---|
Age (mean (SD)) | 62.52 (17.22) | 63.72 (15.02) | 0.074 | 61.94 (16.47) | 63.20 (15.25) | 0.08 |
Gender (%) | 0.109 | 0.015 | ||||
Male | 3079 (55.7) | 1137 (61.1) | 744 (60.0) | 753 (60.7) | ||
Female | 2446(44.3) | 724 (38.9) | 497 (40.0) | 488 (39.3) | ||
GCS (mean (SD)) | 5.74 (1.92) | 4.62 (1.97) | 0.575 | 5.13 (1.98) | 4.74 (2.00) | 0.2 |
Ethnicity (%) | 0.221 | 0.083 | ||||
White | 3892 (71.1) | 1343 (72.4) | 906 (73.0) | 902 (72.7) | ||
Black | 799 (14.6) | 173 (9.3) | 141 (11.4) | 119 (9.6) | ||
Asian | 107 (2.0) | 37 (2.0) | 28 (2.3) | 28 (2.3) | ||
Hispanic | 206 (3.8) | 51 (2.8) | 40 (3.2) | 40 (3.2) | ||
Other | 470 (8.6) | 250 (13.5) | 126 (10.2) | 152 (12.2) | ||
Unit (%) | 0.738 | 0.321 | ||||
CICU | 946 (17.1) | 913 (49.1) | 359 (28.9) | 538 (43.4) | ||
MICU | 1227 (22.2) | 307 (16.5) | 291 (23.4) | 264 (21.3) | ||
MSICU | 1978 (35.8) | 395 (21.2) | 385 (31.0) | 264 (21.3) | ||
NICU | 451 (8.2) | 54 (2.9) | 33 (2.7) | 30 (2.4) | ||
SICU | 923 (16.7) | 192 (10.3) | 173 (13.9) | 145 (11.7) | ||
Primary diagnosis (%) | 0.465 | 0.191 | ||||
Circulatory disease | 2160 (39.1) | 1049 (56.4) | 529 (42.6) | 630 (50.8) | ||
Digestive disease | 179 (3.2) | 74 (4.0) | 60 (4.8) | 54 (4.4) | ||
Endocrine disease | 186 (3.4) | 50 (2.7) | 42 (3.4) | 31 (2.5) | ||
Infectious disease | 391 (7.1) | 175 (9.4) | 146 (11.8) | 155 (12.5) | ||
Injury disease | 733 (13.3) | 154 (8.3) | 160 (12.9) | 119 (9.6) | ||
Mental disease | 61 (1.1) | 11 (0.6) | 10 (0.8) | 8 (0.6) | ||
Neoplasm disease | 157 (2.8) | 41 (2.2) | 30 (2.4) | 29 (2.3) | ||
Nervous disease | 422 (7.6) | 45 (2.4) | 34 (2.7) | 28 (2.3) | ||
Respiratory disease | 743 (13.4) | 126 (6.8) | 118 (9.5) | 97 (7.8) | ||
Urinary disease | 69 (1.2) | 10 (0.5) | 8 (0.6) | 6 (0.5) | ||
Other disease | 424 (7.7) | 126 (6.8) | 104 (8.4) | 84 (6.8) | ||
CCI (mean (SD)) | 4.00 (2.46) | 4.51 (2.41) | 0.209 | 4.23 (2.67) | 4.53 (2.50) | 0.114 |
CHF (%) | 653 (11.8) | 384 (20.6) | 0.241 | 200 (16.1) | 244 (19.7) | 0.093 |
AF (%) | 686 (12.4) | 450 (24.2) | 0.308 | 207 (16.7) | 295 (23.8) | 0.177 |
Renal (%) | 514 (9.3) | 199 (10.7) | 0.046 | 140 (11.3) | 143 (11.5) | 0.008 |
Liver (%) | 181 (3.3) | 82 (4.4) | 0.059 | 75 (6.0) | 70 (5.6) | 0.017 |
COPD (%) | 416 (7.5) | 195 (10.5) | 0.103 | 122 (9.8) | 144 (11.6) | 0.057 |
CAD (%) | 315 (5.7) | 533 (28.6) | 0.639 | 128 (10.3) | 310 (25.0) | 0.392 |
Stroke (%) | 1018 (18.4) | 168 (9.0) | 0.276 | 108 (8.7) | 100 (8.1) | 0.023 |
MT (%) | 436 (7.9) | 158 (8.5) | 0.022 | 116 (9.3) | 116 (9.3) | < 0.001 |
HR (mean (SD)) | 92.80 (24.26) | 91.30 (21.60) | 0.065 | 94.68 (24.81) | 93.07 (22.76) | 0.067 |
MAP (mean (SD)) | 87.32 (25.65) | 80.59 (21.41) | 0.285 | 81.80 (22.41) | 80.37 (21.40) | 0.065 |
Temperature (mean (SD)) | 36.68 (4.12) | 36.24 (2.66) | 0.128 | 36.30 (2.97) | 36.26 (2.46) | 0.016 |
WBC (mean (SD)) | 13.61 (12.62) | 14.56 (11.25) | 0.079 | 14.55 (14.76) | 15.13 (12.44) | 0.043 |
Hemoglobin (mean (SD)) | 11.84 (2.51) | 10.90 (2.52) | 0.373 | 11.31 (2.63) | 10.95 (2.57) | 0.14 |
Platelet (mean (SD)) | 223.01 (105.97) | 199.98 (100.87) | 0.223 | 211.05 (104.75) | 203.36 (104.50) | 0.074 |
Sodium (mean (SD)) | 138.98 (6.56) | 137.96 (5.71) | 0.166 | 138.85 (6.76) | 138.09 (5.83) | 0.12 |
Potassium (mean (SD)) | 4.18 (0.90) | 4.35 (0.93) | 0.192 | 4.28 (1.00) | 4.37 (0.94) | 0.094 |
Bicarbonate (mean (SD)) | 22.80 (5.85) | 22.10 (5.11) | 0.128 | 21.36 (6.02) | 21.61 (5.44) | 0.043 |
Chloride (mean (SD)) | 103.58 (7.70) | 105.68 (7.12) | 0.283 | 104.52 (7.90) | 105.54 (7.39) | 0.133 |
BUN (mean (SD)) | 28.15 (23.83) | 27.21 (21.89) | 0.041 | 30.31 (23.69) | 28.69 (22.48) | 0.07 |
Lactate (mean (SD)) | 4.33 (4.23) | 3.85 (3.38) | 0.128 | 4.22 (3.76) | 3.81 (3.37) | 0.115 |
Sedative (%) | 2113 (38.2) | 1387 (74.5) | 0.786 | 792 (63.8) | 923 (74.4) | 0.23 |
Vasopressor (%) | 1492 (27.0) | 1229 (66.0) | 0.85 | 663 (53.4) | 811 (65.4) | 0.245 |
MV (%) | 4000 (72.4) | 1584 (85.1) | 0.315 | 1033 (83.2) | 1071 (86.3) | 0.085 |
SOFA (mean (SD)) | 7.35 (3.39) | 9.25 (3.51) | 0.549 | 9.40 (3.52) | 9.68 (3.63) | 0.08 |
Database (%) | 0.622 | 0.492 | ||||
MIMIC-IV | 1726 (31.2) | 1132 (60.8) | 450 (36.3) | 746 (60.1) | ||
eICU | 3799 (68.8) | 729 (39.2) | 791 (63.7) | 495 (39.9) |