Variables | Ovarian stimulation protocol | p value | ||
---|---|---|---|---|
PPOS | GnRH agonist | GnRH antagonist | ||
No. of PGT-A cycles | 146 | 160 | 302 | |
Female age (years) | 38(33–41) | 35(32–39) | 37(33–40) | 0.001a,c |
BMI (kg/m2) | 22.05(20.3–24.2) | 21.6(20.3–23.4) | 21.2(19.6–23.2) | 0.010b |
Primary infertility (%)* | 22.6%(33/146) | 11.25%(18/160) | 21.52%(65/302) | 0.013a,c |
Secondary infertility (%)* | 77.4%(113/146) | 88.75%(142/160) | 78.48%(237/302) | 0.013c |
Infertility duration (years) | 1.5(1–3.75) | 2(1–4) | 2(1–3) | 0.896 |
AMH | 2.49(1.12–5.59) | 3.33(2.33–4.76) | 2.7(1.45–4.86) | 0.06 |
bFSH | 7.59(5.6–9) | 6.3(4.98–7.28) | 7.11(5.97–8.52) | 0.000a,c |
AFC | 12(6–20) | 14(10–19) | 11(6–17) | 0.138 |
Indication of PGT-A (%)* | 0.001 | |||
Advanced maternal age | 26.03%(38/146) | 14.38%(23/160) | 24.83%(75/302) | |
Recurrent miscarriage | 19.18%(28/146) | 44.38%(71/160) | 32.78%(99/302) | |
Repeated implantation failure | 25.34%(37/146) | 19.38%(31/160) | 16.89%(51/302) | |
Mixed | 29.45%(43/146) | 21.88%(35/160) | 25.50%(77/302) |