Table 2 Characteristics and outcomes of ovarian stimulation

No. of PGT-A cycles

146

160

302

Total dosage of Gn (IU)

1800(1575–2025)

2550(2071.86–3150)

2025(1593.75–2400)

0.000^a,b,c

Duration of stimulation (days)

8(7–9)

11.5(10–13)

9(8–9)

0.000^a,b,c

Oestradiol level on triggering day (pg/ml)

2420.92(1290–3533.49)

2641(1973.32–3668.44)

2017.36(1268.5–3017)

0.003^c

Serum LH level on trigger day (IU/l)

3(1.94–5)

0.86(0.59–1.68)

2(1–3.29)

0.000^a,b,c

Progesterone level on trigger day (ng/ml)

1(0.77–1)

0.98(0.71–1.26)

1(0.73–1.32)

0.588

Total No. of retrieved oocytes

1280

1892

2999

No. of retrieved oocytes

7(4–12)

12(7–15)

8(5–13)

0.000^a,c

Total No. of MII

1062

1483

2374

No. of MII (n)

6(3–10)

9(6–12)

6(4–11)

0.000^a,c

MII rate (%)

82.97%(1062/1280)

78.38%(1483/1892)

79.16%(2374/2999)

0.004^a,b

Total No. of oocytes fertilised (n)

815

1014

1716

No. of oocytes fertilised (n)

4.5(2–8)

6(3–9)

5(3–8)

0.014^a,c

Oocytes fertilised rate (%)*

76.74%(815/1062)

68.37%(1014/1483)

72.28(1716/2374)

0.000^a,b,c

Total No. of cleaving embryos (n)

793

975

1668

Cleavage rate (%)*

97.3%(793/815)

96.15%(975/1014)

97.2%(1668/1716)

0.24

Total No. of blastocyst culture

765

996

1625

Total No. of blastocysts formation

333

454

723

No. of blastocysts formation (n)

2(0–3)

2(1–4)

2(1–4)

0.036^a,c

Blastocysts formation rate (%)*

43.53%(333/765)

45.58%(454/996)

44.49%(723/1625)

0.687

Total No. of euploid blastocysts

155

209

331

No. of euploid blastocysts (n)

0(0–2)

1(0–2)

1(0–2)

0.084

Euploid blastocysts rate per biopsy (%)*

46.54%(155/333)

46.04%(209/454)

45.78%(331/723)

0.973

Euploid blastocysts rate per injected MII (%)*

14.60%(155/1062)

14.09%(209/1483)

13.94%(331/2374)

0.878

No. of PGT cycle with no blastocyst (%)

28.1%(41/146)

14.38%(23/160)

21.52%(65/302)

0.013^a

No. of PGT cycle with no transferable blastocysts (%)*

51.37%(75/146)

38.75%(62/160)

47.02%(142/302)

0.074