Respiratory viruses and postoperative hemodynamics in patients with unrestrictive congenital cardiac communications: a prospective cohort study

Table 1 Demographic and diagnostic data in patient groups

	Viral genomes in tracheal aspirates
	Absent (n = 34)	Present (n = 21)	p value
Age, months	10 (7–17)	11 (8–15)	0.621^†
Gender, M:F	14:20	7:14	0.767^‡
Weight, kg	6.6 (5.4–8.1)	6.4 (6.0–7.5)	0.993^†
Height, cm	65.0 (61.8–72.5)	66.0 (62.0–70.5)	0.835^†
Down syndrome, n (%)	26 (76.5)	10 (47.6)	0.058^‡
Peripheral oxygen saturation, %	96 (93–98)	96 (92–98)	0.875^†
Transthoracic echocardiography
Main cardiac anomaly, ventricular septal defect: atrioventricular septal defect	19:15	14:7	0.610^‡
Pulmonary/systemic blood flow ratio	2.25 (1.70–3.05)	2.20 (1.55–2.90)	0.597^†
Velocity–time integral of blood flow in pulmonary veins, cm^a	22.4 (18.8–25.3)	21.3 (20.0–25.0)	0.815^†
TAPSE, mm^§	15.0 (13.0–17.0)	13.0 (12.0–16.0)	0.155^†
CPB time, min	132 (90–151)	125 (95–152)	0.979^†
Pre-CPB mean pulmonary artery pressure, mmHg	32 (28–36)	37 (30–40)	0.070^†
Pre-CPB pulmonary/systemic mean arterial pressure ratio	0.79 (0.62–0.86)	0.83 (0.68–0.94)	0.212^†

Numeric variables are presented as median with interquartile range
CPB cardiopulmonary bypass
^†Mann–Whitney test
^‡Chi-square test
^§Tricuspid annular plane systolic excursion. Normally, values increase with increasing age in the pediatric population. A TAPSE of ≥ 15.5 is considered normal at the age of 1 year, as are values ≥ 16.5 by the age of 2 years [24]
^aValues < 20 cm are generally associated with elevated pulmonary vascular resistance in pediatric patients with unrestrictive cardiac shunts [22, 23]

ISSN: 2047-783X