Comparison of the effect of oral and vaginal misoprostol on labor induction: updating a systematic review and meta-analysis of interventional studies

Table 3 Comparison of maternal, neonatal outcomes and adverse effects in two groups

Outcomes	Variables	Effect Size		Heterogeneity Assessment			Publication Bias
Outcomes	Variables	RR	% 95 CI	I² (%)	Q	P value	B	SE	P value
Neonatal	Apgar < 7 in 1 min	0.81	0.70; 0.94	56.58	48.36	0.00	0.57	0.16	0.04
	Apgar < 7 in 5 min	0.72	0.58; 0.88	61.14	48.90	0.00	0.57	0.14	0.03
	IUGR	1.01	0.71; 1.43	40.36	5.70	0.68	0.29	0.85	0.73
	Oligohydramnios	0.96	0.79; 1.16	47.35	6.79	0.75	− 0.51	0.48	0.29
	MSAF	1.32	1.10; 1.57	54.71	39.74	0.07	0.49	0.50	0.33
	Non-FHR	0.89	0.69; 1.16	28.10	13.97	0.17	− 1.27	0.57	0.02
	NICU	0.96	0.80; 1.16	22.30	21.88	0.19	− 0.05	0.47	0.91
Maternal	Neonatal Death	0.60	0.15; 2.48	0.00	0.21	0.90	− 0.09	1.71	0.95
	Tachysystole	0.71	0.60; 0.85	69.14	45.36	0.00	− 1.38	0.44	0.00
	Hypertonus	1.81	1.00; 3.46	0.00	4.80	0.78	0.31	0.95	0.74
	Uterine hyperstimulation	0.82	0.69; 0.97	52.26	39.80	0.00	− 1.01	0.27	0.00
	Preeclampsia	0.72	0.42; 1.24	42.90	7.00	0.14	− 0.78	1.60	0.62
	PROM	1.44	1.20; 1.72	36.66	5.11	0.41	− 0.46	0.90	0.61
	Oxytocin Need	1.11	1.03; 1.20	85.70	77.04	0.00	0.78	0.30	0.01
	Abortion	0.67	0.19; 2.34	0.00	1.69	0.48	1.65	0.17	0.45
	Cesarean	1.04	0.93; 1.16	63.16	65.33	0.00	− 0.36	0.50	0.47
	LSCS	1.50	1.06; 2.12	0.00	0.70	0.95	0.20	1.56	0.89
Adverse effects	Nausea	1.28	1.00; 1.72	35.52	15.51	0.11	0.68	0.13	0.01
	Vomiting	1.32	1.00; 1.74	13.30	12.69	0.31	0.89	0.55	0.11
	Headache	0.74	0.22; 2.24	0.00	0.94	0.62	0.69	0.32	0.45
	Fever	0.98	0.63; 1.52	0.36	7.03	0.44	1.22	1.12	0.27

ISSN: 2047-783X