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Fig. 2 | European Journal of Medical Research

Fig. 2

From: Triple-tyrosine kinase inhibition by BIBF1000 attenuates airway and pulmonary arterial remodeling following chronic allergen challenges in mice

Fig. 2

Inhibition of VEGFR, PDGFR, and FGFR signaling by BIBF1000 reduced lung inflammatory cell accumulation in a mouse model of ovalbumin (OVA) allergen-induced chronic asthma. Inflammatory cell counts for A eosinophils, B neutrophils, C macrophages, D lymphocytes, and levels of E IL-5 and F IL-13 in BAL fluids. All values are mean ± SEM, n = 8. #p < 0.05 vs. control, *p < 0.05 vs. vehicle

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European Journal of Medical Research

ISSN: 2047-783X

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