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Table 4 The predictive efficiency of SWE for NAFLD assessment

From: Diagnostic efficiency on ultrasound shear wave elastography in evaluation of steatosis severity for non-alcoholic fatty liver disease: a rat model

Steatosis

S ≥ S1

S ≥ S2

S = S3

AUC (95%CI)

0.964 (0.917, 1.000)

0.987 (0.963, 1.000)

0.904 (0.812, 0.996)

AUC* (95%CI)

0.956 (0.872, 0.998)

0.987 (0.951, 1.000)

0.920 (0.816, 0.986)

Cutoff

7.35

7.79

8.13

Sensitivity (%)

91.18 (76.32, 98,14)

96.55 (82.24, 99.91)

95.65 (78.05, 99.89)

Specificity (%)

100.00 (76.84, 98.14)

94.74 (73.97, 99.87)

80.00 (59.30, 93.17)

PPV (%)

100.00 (88.78, 100.00)

96.55 (82.24, 99.91)

81.48 (61.92, 93.70)

NPV (%)

82.35 (56.57, 96.20)

94.74 (73.97, 99.87)

95.24 (76.18, 99.88)

Accuracy (%)

93.75 (82.80, 98.69)

95.83 (85.75, 99.49)

87.50 (74.75, 95.27)

  1. Cutoff critical cutoff value, AUC area under the receiver operating characteristic curve, PPV positive predictive value, NPV negative predictive value
  2. AUC* adjusted for inflammation and ballooning
  3. S ≥ S1 fatty liver, S ≥ S2 moderate steatosis or higher severity, S = S3 severe steatosis