Table 1 Demographic and treatment characteristics of patients
Characteristics | Group 1 clinical pregnancy (n = 52) | Group 2 failed pregnancy group (n = 610) | P value |
|---|---|---|---|
Maternal age (years ± SD) | 30.60 ± 3.49 | 31.52 ± 4.48 | 0.257 |
Paternal age (years ± SD) | 31.00 ± 3.77 | 33.00 ± 5.62 | 0.057 |
Maternal BMI (kg/m2) | 22.00 ± 3.37 | 23.21 ± 9.60 | 0.028 |
Infertility duration (years) | 3.63 ± 2.63 | 4.19 ± 3.02 | 0.358 |
Infertility cause, n (%) | 0.461 | ||
Female | 31 (59.62) | 397 (65.08) | |
Male | 5 (9.61) | 75 (12.30) | |
Mixed | 14 (26.92) | 128 (20.98) | |
Unexplained | 2 (3.85) | 10 (1.64) | |
Type of infertility, n (%) | 0.419 | ||
Primary | 27 (51.92) | 352 (57.70) | |
Secondary | 25 (48.08) | 258 (42.30) | |
Gravidity, n (%) | 0.173 | ||
0 | 21 (40.38) | 332 (54.43) | |
1 | 15 (28.85) | 146 (23.93) | |
> 1 | 16 (30.77) | 132 (21.64) | |
Parity, n (%) | 0.234 | ||
0 | 39 (75.00) | 478 (78.36) | |
1 | 12 (23.08) | 130 (21.31) | |
> 1 | 1 (1.92) | 2 (0.33) | |
ET cycles | 0.137 | ||
1 | 25 (48.08) | 366 (60.00) | |
2 | 16 (30.77) | 167 (27.38) | |
> 2 | 11 (21.15) | 77(12.62) | |
Procedure | 0.238 | ||
IVF | 37 (71.15) | 384 (62.95) | |
ICSI | 15 (28.85) | 226 (37.05) | |
Basal FSH (IU/L) | 7.09 ± 2.77 | 8.33 ± 6.91 | 0.029 |
Basal LH (IU/L) | 4.78 ± 3.57 | 8.33 ± 6.92 | 0.168 |
Basal E2 (pmol/L) | 172.79 ± 111.00 | 179.00 ± 172.91 | 0.722 |
E2 on hCG (pmol/L) | 12,252.98 ± 5863.05 | 10,587.24 ± 5950.73 | 0.038 |
LH on hCG (IU/L) | 2.86 ± 3.18 | 3.51 ± 5.77 | 0.290 |
P on hCG (nmol/L) | 5.29 ± 4.00 | 4.74 ± 4.55 | 0.263 |
Retrieved oocytes | 11.77 ± 7.38 | 10.05 ± 6.54 | 0.054 |
Endometrial preparation | 0.008 | ||
Natural cycles | 8 (15.38) | 202 (33.11) | |
Artificial cycle | 44 (84.62) | 408 (66.89) | |
Endometrial thickness (mm) | 10.56 ± 1.59 | 10.70 ± 1.80 | 0.986 |
Number of blastocysts, n (%) | 0.913 | ||
1 | 9 (17.31) | 102 (16.72) | |
≥ 2 | 43 (82.69) | 508 (83.27) | |
Blastocyst day, n (%) | 0.00 | ||
D5 | 14 (26.92) | 56 (9.18) | |
D6 | 38 (73.08) | 554 (90.82) | |
Blastocyst score, n (%) | 0.712 | ||
3BC or 3CB | 36 (69.23) | 451 (73.93) | |
3CC | 14 (26.92) | 134 (21.97) | |
< 3CC | 2 (3.85) | 25 (4.1) |