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Fig. 5 | European Journal of Medical Research

Fig. 5

From: Role of hyperbaric oxygen therapy in PDGF-BB-mediated astrogliosis in traumatic brain injury rats associated with ERK1/2 signaling pathway inhibition

Fig. 5

HBO inhibited the proliferation of astrocytes in TBI rats and promoted the regeneration of neurons. AD Results of GFAP, NeuN, SYP, and TUNEL staining in the damaged cerebral cortex among the Sham, TBI, and HBO groups (100× , Scale bars = 100um). E The western blotting results and the relative protein expression levels of PDGF-BB and phosphorylated ERK1/2 (p-ERK1/2) at 7 d and 14 d after TBI among the Sham, Injury, and HBO groups. F Comparison of the relative mRNA expression levels of PDGF-BB and ERK1/2 at 7 d and 14 d after TBI among the Sham, Injury, and HBO groups. *P < 0.05, vs. Sham group, #P < 0.05, vs. TBI group

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