Table 2 Univariate Cox analysis of clinical outcomes in peritoneal dialysis patients
From: The prognostic value of monocyte-to-lymphocyte ratio in peritoneal dialysis patients
Variables | All-cause mortality | new-onset CVD events | ||
|---|---|---|---|---|
Univariate analysis | Univariate analysis | |||
HR (95% CI) | P-value | HR (95% CI) | P-value | |
Gender (male) | 0.773 (0.471, 1.268) | 0.308 | 0.777 (0.554, 1.090) | 0.144 |
Age (≥ 60 years old) | 4.487 (2.728, 7.379) | < 0.001 | 2.514 (1.798, 3.515) | < 0.001 |
BMI (kg/m2) | 1.078 (0.995, 1.167) | 0.065 | 1.095 (1.037, 1.157) | 0.001 |
SBP (mmHg) | 1.006 (0.995, 1.016) | 0.301 | 1.010 (1.003, 1.017) | 0.008 |
DBP (mmHg) | 0.989 (0.973, 1.006) | 0.199 | 0.993 (0.982, 1.005) | 0.261 |
Diabetes mellitus | 3.687 (2.146, 6.335) | < 0.001 | 3.437 (2.348, 5.031) | < 0.001 |
Current smoking | 2.132 (1.195, 3.804) | 0.010 | 1.605 (1.046, 2.462) | 0.030 |
CVD history | 3.033 (1.738, 5.292) | < 0.001 | 2.461 (1.615, 3.748) | < 0.001 |
White blood count (× 109/L) | 1.064 (0.961, 1.178) | 0.230 | 1.090 (1.013, 1.173) | 0.022 |
Hemoglobin (g/dL) | 1.040 (1.007, 1.075) | 0.018 | 1.028 (1.001, 1.056) | 0.045 |
Platelet count (× 109/L) | 1.006 (1.003, 1.010) | 0.001 | 1.004 (1.001, 1.007) | 0.003 |
Neutrophil count (× 109/L) | 1.081 (0.975, 1.198) | 0.138 | 1.088 (1.006, 1.177) | 0.034 |
Lymphocyte count (× 109/L) | 0.736 (0.435, 1.245) | 0.253 | 1.065 (0.766, 1.479) | 0.709 |
Monocyte count (× 109/L) | 2.095 (0.623, 7.047) | 0.232 | 2.265 (1.066, 4.811) | 0.033 |
MLR (> 0.2168) | 2.983 (1.284, 6.931) | 0.011 | 2.010 (1.285, 3.146) | 0.002 |
Albumin (g/L) | 0.976 (0.929, 1.026) | 0.338 | 0.954 (0.922, 0.986) | 0.006 |
Globulin (g/L) | 1.056 (1.007, 1.106) | 0.024 | 1.035 (1.000, 1.071) | 0.050 |
BUN (mmol/L) | 0.978 (0.953, 1.004) | 0.101 | 0.992 (0.975, 1.008) | 0.315 |
Serum creatinine (μmol/L) | 0.999 (0.998, 1.000) | 0.035 | 1.000 (0.999, 1.000) | 0.616 |
Uric acid (μmol/L) | 0.999 (0.997, 1.001) | 0.161 | 1.000 (0.999, 1.002) | 0.510 |
RRF (ml/min/1.73m2) | 1.051 (0.933, 1.183) | 0.413 | 0.977 (0.898, 1.063) | 0.587 |
Corrected calcium (mmol/L) | 1.047 (0.507, 2.161) | 0.902 | 0.854 (0.534, 1.367) | 0.510 |
Phosphate (mmol/L) | 0.892 (0.597, 1.333) | 0.577 | 0.998 (0.761, 1.308) | 0.986 |
iPTH (Pg/mL) | 1.000 (0.999, 1.001) | 0.537 | 1.000 (0.999, 1.000) | 0.182 |
Prealbumin (mg/L) | 0.992 (0.988, 0.996) | < 0.001 | 0.997 (0.994, 1.000) | 0.030 |
CRP (mg/L) | 1.021 (1.008, 1.034) | 0.002 | 1.012 (1.001, 1.022) | 0.027 |
Cholesterol (mmol/L) | 1.274 (1.035, 1.567) | 0.022 | 1.305 (1.138, 1.497) | < 0.001 |
Triglyceride (mmol/L) | 1.009 (0.806, 1.263) | 0.939 | 1.229 (1.089, 1.389) | 0.001 |
HDL-C (mmol/L) | 1.439 (0.659, 3.144) | 0.362 | 0.691 (0.382, 1.250) | 0.221 |
LDL-C (mmol/L) | 1.555 (1.156, 2.092) | 0.004 | 1.279 (1.047, 1.563) | 0.016 |
apo-A1 (g/L) | 1.219 (0.309, 4.804) | 0.777 | 1.885 (0.812, 4.378) | 0.140 |
apo-B (g/L) | 3.840 (1.546, 9.541) | 0.004 | 2.877 (1.608, 5.149) | < 0.001 |