Clinical predictors of early surgical intervention in patients with venomous snakebites

Table 4 Surgical management and outcomes of 32 patients who underwent surgery for snakebites

Outcomes	Operated cases within 24 h (n = 15)	Operated cases later than 24 h (n = 17)	p value
Total antivenom dose in vials, median (IQR)	5 (0–17)	6 (3–18)	0.529^c
After bite to first surgery in days, median (IQR)	0.5 (0.5–1.0)	5.0 (1.5–15.0)	< 0.001^c
Times of operation for debridement, median (IQR)	2 (0–5)	4 (1–10)	0.012^c
Days of application NPWT dressing, median (IQR)	6 (2–15)	15 (3–42)	0.006^c
Toe or finger amputation, n (%)	2 (13.3%)	4 (23.5%)	0.002^b
Final reconstructive surgery, n (%)			0.028^a
Secondary healing	1 (6.7%)	3 (17.6%)	0.603^b
Delayed primary closure	8 (53.3%)	4 (23.5%)	0.082^b
Delayed primary closure + STSG	3 (20%)	1 (5.9%)	0.319^b
STSG	0	8 (47.1%)	0.003^b
Local flap + STSG	2 (13.3%)	1 (6.3%)	0.589^b
Free flap	1 (6.7%)	0 (17.6%)	0.469^b
LOS(day), median (IQR)	13 (5–27)	26 (10–54)	0.002^c
Outpatient follow-up in days, median (IQR)	15 (7–22)	36 (18–137)	< 0.001^c

h: hour, LOS: length of hospital stay, STSG: split-thickness skin graft, NPWT: negative pressure wound therapy
^aChi-squared test
^bFisher’s exact test
^cMann–Whitney U test

ISSN: 2047-783X