Table 1 Clinicopathological variables associated with corticosteroid response in IgAN patients
Variables | Remission | Non-remission | P value |
|---|---|---|---|
Number | 159 | 86 | – |
Age (years) | 37.7 ± 7.2 | 40.8 ± 8.4 | 0.003* |
Gender, n (%) | – | – | 0.803 |
Male | 84(52.8) | 44(51.2) | – |
Female | 75(47.2) | 42(48.8) | – |
MAP (mmHg) | 95.4 ± 10.1 | 93.1 ± 11.2 | 0.103 |
SBP (mmHg) | 126.6 ± 11.8 | 131.3 ± 12.1 | 0.004* |
DBP (mmHg) | 83.2 ± 9.9 | 82.7 ± 10.1 | 0.708 |
History of macroscopic haematuria, n (%) | 19(11.9) | 16(18.6) | 0.155 |
Oxford classification, n (%) | |||
M1 | 44(27.8) | 35(40.7) | 0.037* |
E1 | 39(24.5) | 33(38.4) | 0.023* |
S1 | 79(49.7) | 52(60.5) | 0.106 |
T1-T2 | 43(27.0) | 28(32.6) | 0.364 |
C1-C2 | 56(35.2) | 48(55.8) | 0.002* |
Current smoking, n (%) | 8(5.0) | 6(7.0) | 0.531 |
Diabetes, n (%) | 27(17.0) | 16(18.6) | 0.750 |
Hypertension, n (%) | 43(27.0) | 27(31.4) | 0.472 |
Medications, n (%) | – | – | – |
ACEI | 16(10.1) | 8(9.3) | 0.848 |
ARB | 128(80.5) | 69(80.2) | 0.959 |
SGLT2 inhibitor | 53(33.3) | 33(38.4) | 0.430 |
3-year prognosis, n (%) | – | – | – |
50% decline in eGFR | 16/128 (12.5) | 17/61 (27.9) | 0.009* |
Kidney failure | 14/128 (10.9) | 15/61 (24.6) | 0.015* |