Skip to main content

Table 3 Risk factors for corticosteroid response in IgAN patients by univariate and multiple Cox regression analyses

From: Albumin-to-fibrinogen ratio is an independent predictor of corticosteroid response and prognosis in patients with IgA nephropathy

Variables

Univariate multivariate

HR(95%CI)

p value

HR(95%CI)

p value

Age (high vs low)

2.11(1.03–4.39)

0.041*

1.52(0.92–2.48)

0.088

SBP (high vs low)

1.73(0.86–3.49)

0.125

  

History of macroscopic haematuria (yes vs no)

0.86(0.58–1.19)

0.308

  

Oxford classification

 M0 vs M1

1.15(1.06–1.27)

0.009*

0.93(0.78–1.12)

0.446

 E0 vs E1

1.21(0.51–2.71)

0.671

  

 C0 vs C1/C2

2.55(1.20–5.47)

0.011*

2.34(1.32–4.15)

0.018*

Uric acid (high vs low)

1.46(0.61–3.57)

0.377

  

eGFR (≥ 78.1 vs < 78.1)

2.22(1.32–3.73)

0.003*

1.98(1.31–2.98)

0.012*

Serum creatinine (high vs low)

0.51(0.24–1.11)

0.094

  

AFR (≥ 7.53 vs < 7.53)

3.63 (1.44–8.68)

0.005*

2.38(1.32–4.07)

0.015*

  1. SBP systolic blood pressure; IgAN Immunoglobulin A (IgA) nephropathy; AFR albumin-to-fibrinogen ratio; eGFR estimated glomerular filtration rate; HR hazard ratio; CI confidence interval
  2. *P < 0.05