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Table 2 Evaluation of AAGN patients with RRS and RVLs score

From: Evaluation of three scoring systems for predicting renal prognosis in antineutrophil cytoplasmic antibody-associated glomerulonephritis

 

RRS Group

Low

Medium

High

P

SCr (μmol/L)

147.5 (108.8, 196.3)b

363.0 (247.0, 493.0)ab

673.0 (510.0, 780.0)a

 < 0.001

eGFR (ml/min/1.73 m2)

41.9 (30.2, 64.4)b

12.2 (8.8, 17.5)ab

6.6 (5.3, 9.0)a

 < 0.001

Dialysis at diagnosis (n, %)

0 (0)b

25 (58.1)a

13 (86.7)a

 < 0.001

SBP (mmHg)

125 (120, 160)b

150(130, 180)a

151 (136, 180)a

0.004

Normal glomeruli (%)

58.0 (40.4, 79.2)b

20.0 (12.8, 38.5)ab

5.1 (2.7, 10.0)a

 < 0.001

fibrocellular crescent (%)

0 (0, 10.0)b

10.0 (0, 26.8)a

5.9 (0, 16.0)a

0.011

 

RVLs Group

Without

Mild

Moderate

Severe

P

SCr (μmol/L)

166.0 (118.0, 198.5)b

207.0 (132.0, 414.0)b

344.0 (182.0, 475.5)ab

532.0 (347.5, 752.0)a

 < 0.001

eGFR (ml/min/1.73 m2)

37.8 (27.5, 48.0)b

25.5 (10.5, 42.0)b

13.8 (9.7, 26.9)a

8.0 (5.8, 13.6)a

 < 0.001

Dialysis at diagnosis (n, %)

1 (7.7)b

11 (28.2)b

14 (48.3)b

12 (93.2)a

 < 0.001

SBP (mmHg)

130 (123, 159)b

134 (120, 160)b

150 (128, 180)

180 (146, 188)a

0.004

Normal glomeruli (%)

60.0(39.3, 78.8)b

33.3 (16.7, 59.6)ab

20.0 (11.8, 52.5)a

12.5 (5.2, 31.7)a

0.004

fibrocellular crescent (%)

0 (0, 2.2)b

8.9 (0, 22.0)a

2.4 (0, 10.3)b

14.3 (6.5, 28.0)a

0.007

  1. Data are displayed as the median (interquartile range)
  2. RRS renal risk score, RVLs renal vascular lesions, SCr serum creatinine, eGFR estimated glomerular filtration rate, SBP systolic blood pressure
  3. aIndicates P < 0.05 compared with the group with Low RRS or without RVLs
  4. bIndicates P < 0.05 compared with the group with High RRS or severe RVLs