Table 1 Baseline characteristics of the patients
Characteristic | All cases (n = 220) | Control group (n = 102) | Study group (n = 118) | Z/χ2 | P-Value |
|---|---|---|---|---|---|
Age (IQR)/year | 65.50 (58.00, 76.00) | 65.00 (57.75–76.00) | 66.00 (58.00–76.00) | −0.082 | 0.935 |
Female (n, %) | 53 (24.09) | 25 (24.51) | 28 (23.73) | 0.018 | 0.893 |
SBP (IQR)/mmHg | 154.00 (140.00, 172.0) | 155.50 (138.00–176.00) | 154.00 (142.75–170.50) | −0.398 | 0.690 |
DBP (IQR)/mmHg | 90.00 (80.00, 103.00) | 89.00 (77.50–103.00) | 90.00 (81.00–103.00) | −1.113 | 0.266 |
OMT (IQR)/h | 16.00 (5.00, 36.00) | 13.00 (4.75–27.00) | 18.00 (5.00–48.00) | −0.761 | 0.447 |
bNIHSS (IQR) | 4.00 (3.00, 5.00) | 4.00 (3.00–5.00) | 4.00 (3.00–4.25) | −1.223 | 0.221 |
Medical history (n, %) | |||||
Hypertension | 184 (83.64) | 85 (83.33) | 99 (83.90) | 0.013 | 0.910 |
Diabetes | 93 (42.27) | 45 (44.12) | 48 (40.68) | 0.265 | 0.607 |
Hyperlipidemia | 38 (17.27) | 19 (18.63) | 19 (16.10) | 0.244 | 0.621 |
Atrial fibrillation | 31 (14.09) | 16 (15.69) | 15 (12.71) | 0.400 | 0.527 |
Prior ischemic stroke | 69 (31.36) | 32 (31.37) | 37 (31.36) | 0.000 | 0.998 |
Prior antiplatelet | 72 (32.73) | 37 (36.27) | 35 (29.66) | 1.087 | 0.297 |
Median baseline of various enzymology before medication (IQR) – U/L | |||||
ALT | 16.80 (12.20, 23.40) | 17.55 (11.95–25.08) | 16.45 (12.73–22.30) | −0.238 | 0.812 |
AST | 16.60 (12.80, 21.65) | 15.95 (11.78–20.93) | 17.15 (13.55–22.00) | −1.494 | 0.135 |
LDH | 171.00 (149.00, 200.00) | 173.50 (150.00–200.00) | 170.00 (147.50–200.25) | −0.713 | 0.476 |
CK | 74.50 (54.25, 105.50) | 75.50 (58.75–113.25) | 74.50 (52.00–101.25) | −0.825 | 0.409 |
Median of various enzymology in 2 weeks (14 ± 3 d) after medication (IQR) – U/L | |||||
ALT | 17.35 (12.03, 27.18) | 18.15 (12.00–27.70) | 16.85 (12.00–25.68) | −0.832 | 0.406 |
AST | 16.40 (13.20, 21.78) | 16.10 (13.00–21.25) | 16.85 (13.28–22.03) | −0.658 | 0.510 |
LDH | 168.00 (151.00, 187.00) | 168.00 (152.75–187.00) | 168.00 (147.50–188.25) | −0.219 | 0.827 |
CK | 71.00 (46.25, 100.00) | 66.00 (46.00–95.25) | 72.00 (49.00–102.25) | −1.165 | 0.244 |