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Table 1 General characteristics of study population according to different metabolic phenotypes

From: Association between thyroid function and obesity phenotypes in healthy euthyroid individuals: an investigation based on Tehran Thyroid Study

Variable

Total (n = 2988)

MHNW (n = 868)

MUNW (n = 363)

MHO (n = 660)

MUO (n = 1097)

P value

Gender, n (%)

      

 Male

1360 (45.5)

391 (45.0)

231 (63.6)

211 (32.0)

527 (48.0)

 < 0.001

 Female

1628 (54.5)

477 (55.0)

132 (36.4)

449 (68.0)

570 (52.0)

Age, years

37.58 (12.21)

32.05 (11.40)bcd

39.43 (12.82)acd

37.12 (10.60)abd

41.63 (11.80)abc

 < 0.001

BMI, kg/m2

26.28 (4.49)

21.83 (2.11)bcd

22.99 (1.73)acd

28.66 (3.27)abd

29.46 (3.36)abc

 < 0.001

WC, cm

86.41 (11.77)

75.46 (7.22)bcd

80.82 (6.86)acd

90.06 (9.47)abd

94.73 (9.19)abc

 < 0.001

TC, mg/dL

199.21 (41.55)

178.58 (34.46)bcd

200.92 (39.84)ad

198.50 (35.91)ad

215.40 (43.18)abc

 < 0.001

TG, mg/dL

135.0 (90.0, 194.0)

86.0 (65.0, 110.7)bcd

179.5 (154.0, 231.0)acd

106.0 (82.0, 132.0)abd

195.0 (158.0, 250.5)abc

 < 0.001

HDL, mg/dL

41.93 (11.07)

47.55 (10.52)bd

35.73 (7.51)ac

46.46 (11.45)bd

36.81 (8.52)ac

 < 0.001

LDL, mg/dL

126.56 (35.29)

112.60 (31.33)bcd

126.01 (33.75)ac

129.65 (31.32)ab

136.47 (37.49)abc

 < 0.001

SBP, mmHg

114.78 (15.52)

107.58 (10.93)bcd

115.68 (15.53)acd

111.12 (12.14)abd

122.43 (16.91)abc

 < 0.001

DBP, mmHg

76.01 (10.25)

70.77 (8.07)bcd

76.11 (10.28)acd

74.26 (8.46)abd

81.21 (10.30)bc

 < 0.001

FPG, mg/dL

88.99 (8.95)

85.72 (6.96)bcd

89.71 (9.59)acd

87.14 (7.26)abd

92.45 (9.79)abc

 < 0.001

Cr, μmol/L

1.03 (0.15)

1.02 (0.15)bd

1.06 (0.14)ac

1.02 (0.14)bd

1.05 (0.15)ac

 < 0.001

eGFR, mL/min/1.73

80.05 (12.28)

84.57 (12.31)

80.37 (12.71)

78.34 (10.87)

77.39 (11.90)

 < 0.001

Smoking, n (%)

      

 Current

383 (12.8)

115 (13.3)

61 (16.8)

60 (9.1)

147 (13.4)

0.003

 Former or never

2598 (87.2)

749 (86.7)

302 (83.2)

599 (90.9)

948 (86.6)

Physical activity, n (%)

      

 Low

2032 (68.4)

589 (68.2)

233 (64.4)

448 (68.3)

762 (69.9)

0.273

 High

940 (31.6)

275 (31.8)

129 (35.6)

208 (31.7)

328 (30.1)

  1. Continuous variables with normal distribution were reported as mean ± SD; Continuous variables with non-normal distribution were reported as median (interquartile range); Categorical variables were reported as n (%)
  2. MHNW, metabolically healthy normal weight; MHO, metabolically healthy overweight/obese; MUNW, metabolically unhealthy normal weight; MUO, metabolically unhealthy overweight/obese; BMI, body mass index; WC, waist circumference; TG, triglycerides; TC, total cholesterol; LDL, low density lipoprotein-cholesterol; HDL, high density lipoprotein-cholesterol; FPG, fasting plasma glucose; SBP, systolic blood pressure; DBP, diastolic blood pressure; FT4, free thyroxine; TPO-Ab, thyroid peroxidase antibody; Cr, creatinine; eGFR, estimated glomerular filtration rate
  3. *Difference between groups, P value is reported based on the one-way ANOVA for normally distributed continuous variables, Kruskal–Wallis for non-normally distributed continuous variables, and Chi-square for categorical variables. A Bonferroni post hoc test was used to show differences between groups
  4. aSignificant difference with MHNW
  5. bSignificant difference with MUNW
  6. cSignificant difference with MHO
  7. dSignificant difference with MUO
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European Journal of Medical Research

ISSN: 2047-783X

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