Photodistributed Stevens–Johnson syndrome and toxic epidermal necrolysis: a systematic review and proposal for a new diagnostic classification

Table 5 Evidence of photosensitive reactions from drugs recognized in causing photodistributed Steven’s–Johnson syndrome and toxic epidermal necrolysis

Drug name	Photosensitivity (non-specific)	Phototoxicity	Photoallergy
Chloroquine ^asulfadoxine –pyrimethamine		[56] [52, 57, 58] [60]	[58, 59]
Carbamazepine	[61,62,63]
Chlorpromazine	[65]	[57, 66, 67]	[57, 68]
Ciprofloxacin		[52, 57, 58, 65, 69]
Clobazam		[70]
Hydroxychloroquine	[65]	[71]	[58, 71]
Ibuprofen	[73, 74]	[52, 57, 58, 65, 72]
Itraconazole	[75]	[52, 57, 65]	[52, 65]
Lamotrigine	[76]	[77]
Naproxen sodium		[52, 57, 58, 65, 78]	[58, 59]
Sulfasalazine		[57]
Tramadol	[80]

^aSulfadoxine is a sulfonamide. Thus, sulfonamide was used to search for photosensitive reactions

ISSN: 2047-783X