Table 3 DNA methylation ages at baseline and post-intervention
From: Exercise and epigenetic ages in older adults with myeloid malignancies
Baseline ages (N = 20) | Statistics | Baseline | Post-intervention | Change | P* |
|---|---|---|---|---|---|
Chronological age | Mean (SD) | 71.7 (4.9) | 71.9 (4.8) | Â | Â |
Median (IQR) | 72.4 (6.5) | 72.6 (6.5) | Â | Â | |
Horvath age | Mean (SD) | 70.8 (9.3) | 70.3 (9.7) | − 0.5 (5.6) |  |
Median (IQR) | 69.6 (13.4) | 68.7 (15.1) | − 0.8 (7.4) | 0.73 | |
Hannum age | Mean (SD) | 58.4 (9.1) | 58.7 (8.6) | 0.3 (10.2) | Â |
Median (IQR) | 59.1 (7.5) | 57.6 (11.4) | − 0.7 (10.8) | 0.57 | |
IEAA | Mean (SD) | − 1.0 (7.9) | − 1.6 (7.8) | − 0.7 (4.1) |  |
Median (IQR) | − 3.0 (10.3) | − 1.8 (11.4) | − 1.0 (5.3) | 0.43 | |
EEAA | Mean (SD) | − 1.2 (10.8) | − 1.0 (11.2) | 0.2 (12.5) |  |
Median (IQR) | − 0.6 (14.1) | − 0.1 (15.8) | − 0.7 (13.7) | 0.81 | |
GrimAge | Mean (SD) | 73.2 (6.8) | 72.5 (5.7) | − 0.7 (4.7) |  |
Median (IQR) | 73.5 (8.1) | 72.3 (6.9) | − 1.4 (4.5) | 0.17 | |
PhenoAge | Mean (SD) | 58.2 (9.7) | 57.4 (8.5) | − 0.8 (12.1) |  |
Median (IQR) | 57.2 (14.9) | 57.0 (6.9) | − 1.4 (12.4) | 0.35 | |
DunedinPACE | Mean (SD) | 1.2 (0.3) | 1.2 (0.2) | 0.02 (0.34) | Â |
Median (IQR) | 1.1 (0.4) | 1.2 (0.3) | − 0.1 (0.2) | 0.47 |