Table 5 Subgroup analysis evaluating change in accelerated DNA methylation age from baseline to post-intervention compared by change in daily steps or minutes of resistance exercise
From: Exercise and epigenetic ages in older adults with myeloid malignancies
ΔDNAm accelerated age | Statistic | Increase in steps from baseline to post-intervention (≥ median) n = 9 | Increase in steps from baseline to post-intervention (< median) n = 9 | P* | Increase in minutes from baseline to post-intervention (≥ median) n = 9 | Increase in minutes from baseline to post-intervention (< median) n = 10 | P* |
|---|---|---|---|---|---|---|---|
ΔPhenoAge | Mean (SD) | − 2.83 (8.89) | − 0.82 (10.56) |  | 2.86 (15.02) | − 3.15 (9.27) |  |
Median (IQR) | − 5.58 (11.63) | − 0.05 (7.90) | 0.79 | − 1.55 (12.56) | − 3.08 (17.52) | 0.71 | |
ΔGrimAge | Mean (SD) | − 1.98 (3.22) | 1.83 (5.68) |  | − 0.10 (5.42) | − 0.04 (4.37) |  |
Median (IQR) | − 2.66 (4.06) | 0.79 (2.85) | 0.08 | − 0.32 (2.65) | − 0.30 (4.93) | 0.90 | |
ΔDunedinPACE | Mean (SD) | − 0.13 (0.28) | 0.08 (0.29) |  | 0.10 (0.40) | − 0.05 (0.31) |  |
Median (IQR) | − 0.18 (0.27) | − 0.03 (0.13) | 0.13 | − 0.05 (0.15) | − 0.07 (0.22) | 0.49 |