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Table 2 Results of univariate and multivariate Cox proportional hazards model applied to assess predictors of all-cause mortality

From: Normal thyroid stimulating hormone is associated with all-cause mortality in patients with acute myocardial infarction after percutaneous coronary intervention

Variables

Univariate analysis HR[95%CI]

P-value

Multivariate analysis HR[95%CI]

P-value

TSH, categorical

 1st

Ref.

–

Ref.

–

 2nd

1.19[0.81,1.74]

0.384

1.11[0.75,1.65]

0.605

 3rd

2.01[1.42,2.85]

 < 0.001

1.56[1.08,2.25]

0.017

 Age > 65 years

3.64[2.46,5.37]

 < 0.001

1.87[1.15,3.02]

0.011

 Male

0.59[0.43,0.8]

0.001

1.04[0.72,1.50]

0.822

 Hypertension

1.53[1.14,2.06]

0.005

1.21[0.87,1.67]

0.259

 Diabetes mellitus

1.76[1.3,2.38]

 < 0.001

1.51[1.09,2.10]

0.013

 Smoking history

1.01[0.76,1.35]

0.918

1.23[0.91,1.66]

0.178

 Hyperlipidaemia

0.85[0.64,1.14]

0.278

0.93[0.69,1.25]

0.638

 Chronic kidney disease

4.86[3.59,6.58]

 < 0.001

2.09[1.46,2.98]

 < 0.001

 Previous coronary heart disease

2.01[1.22,3.31]

0.006

1.10[0.65,1.85]

0.718

 Killip class ≥ II

3.39[2.55,4.5]

 < 0.001

2.05[1.50,2.82]

 < 0.001

 LVEF ≤ 40%

3.07[2.27,4.14]

 < 0.001

2.28[1.67,3.12]

 < 0.001

 Beta-Blockers

0.56[0.42,0.77]

 < 0.001

0.88[0.63,1.22]

0.443

 ACEI/ARBs

0.46[0.35,0.61]

 < 0.001

0.52[0.38,0.70]

 < 0.001

 Statins

0.66[0.31,1.41]

 < 0.001

0.99[0.45,2.18]

0.981

 Three-vessel disease

1.91[1.43,2.55]

 < 0.001

1.47[1.09,2.00]

0.012

 High risk status

3.36[2.45,4.62]

 < 0.001

1.52[1.02,2.26]

0.04

  1. TSH, thyroid stimulating hormone; LVEF, left ventricular ejection fraction; ACEI/ARB, angiotensin converting enzyme inhibitor/angiotensin receptor blocker; HR, hazard ratio; CI, confidence interval