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Table 3 Subgroup analysis on all-cause mortality across tertiles of TSH levels

From: Normal thyroid stimulating hormone is associated with all-cause mortality in patients with acute myocardial infarction after percutaneous coronary intervention

TSH tertiles

No. of patients with events (%)

Adjusted HR [95% CI]

P for interaction

1st tertile

2nd tertile

3rd tertile

1st tertile

2nd tertile

3rd tertile

Total

49(11.8)

56(13.4)

90(21.9)

Ref.

1.11[0.75,1.65]

1.56[1.08,2.25]

 

Age

      

0.34

  > 65 years

38(17.1)

50(19.3)

77(28.3)

Ref.

1.18[0.76,1.83]

1.53[1,02,2.30]

 

  ≤ 65 years

11(5.7)

6(3.7)

13(9.4)

Ref.

0.62[0.21,1.83]

1.40[0.53,3.70]

 

Sex

      

0.555

 Male

39(10.5)

43(12.9)

59(19.6)

Ref.

1.24[0.80,1.94]

1.59[1.04,2.43]

 

 Female

10(23.2)

13(15.4)

31(28.1)

Ref.

0.68[0.27,1.68]

1.08[0.49,2.4]

 

Diabetes

      

0.944

 Yes

15(17.4)

15(19.4)

30(29.7)

Ref.

0.97[0.44,2.13]

1.23[0.6,2.55]

 

 No

34(10.3)

41(12.0)

60(19.4)

Ref.

1.29[0.81,2.07]

1.73[1.11,2.69]

 

Hypertension

      

0.729

 Yes

31(12.6)

39(16.5)

59(26.2)

Ref.

1.39[0.85,2.26]

1.82[1.15,2.87]

 

 No

18(10.7)

17(9.3)

31(16.7)

Ref.

0.62[0.32,1.24]

0.97[0.52,1.82]

 

Clinical presentation

      

0.380

 STEMI

41(11.6)

45(12.4)

76(22.8)

Ref.

1.06[0.69,1.64]

1.76[1.18,2.63]

 

 NSTEMI

8(13.1)

11(20.0)

14(17.9)

Ref.

1.41[0.51,3.93]

1.65[0.70,3.89]

 

GRACE score

      

0.019

 High risk

30(16.9)

38(18.7)

75(35.7)

Ref.

1.27[0.77,2.01]

2.02[1.29,3.16]

 

 Low/medium risk

19(8.0)

18(8.4)

15(7.5)

Ref.

0.93[0.47,1.83]

0.69[0.33,1.45]

 
  1. GRACE score- Global Registry of Acute Coronary Events score; TSH- thyroid stimulating hormone; HR- hazard ratio; CI- confidence interval