Risk factors for clinical progression in patients with pulmonary Mycobacterium avium complex disease without culture-positive sputum: a single-center, retrospective study

Table 2 Microbiological profiles of bronchoscopic specimens at the time of diagnosis

Bacteria	Overall (N = 93)	Stable group (N = 41)	Progressive group (N = 52)	P value
NTM species				0.404
M. avium	63 (67.7)	29 (70.7)	34 (65.4)
M. intracellulare	29 (31.2)	11 (26.8)	18 (34.6)
M. avium and M. intracellulare	1 (1.1)	1 (2.4)	0 (0)
AFB smear-negative	65 (69.9)	28 (68.3)	37 (71.2)	0.765
AFB smear-positive (grade 1+)	28 (30.1)	13 (31.7)	15 (28.8)
AFB smear-positive (grade ≥ 2+)	0 (0)	0 (0)	0 (0)
Time to culture positive (week)	1 (1–1)	0 (0–1)	1 (0–1)	0.355
Other species
S. aureus	21 (22.6)	9 (22.0)	12 (23.1)	0.897
Veillonella species	53 (57.0)	24 (58.5)	29 (58.5)	0.789
Aspergillus species	13 (14.0)	7 (17.1)	6 (11.5)	0.445
P. aeruginosa	8 (8.6)	3 (7.3)	5 (9.6)	0.695

NTM, nontuberculosis mycobacteria; M. avium, Mycobacterium avium
M. intracellulare, Mycobacterium intracellulare; AFB, acid-fast bacilli; S. aureus, Staphylococcus aureus; P. aeruginosa, Pseudomonas aeruginosa. Categorical variables are represented as absolute numbers (%). Medians (interquartile range) are used to describe non-parametric data. Categorical variables were analyzed using the Chi-squared test. Non-parametric data were analyzed by the Mann–Whitney U test. P values are for comparisons between stable group and progressive group

ISSN: 2047-783X