Risk factors for clinical progression in patients with pulmonary Mycobacterium avium complex disease without culture-positive sputum: a single-center, retrospective study

Table 4 Univariate and multivariate analyses of risk factors for progression in the study subjects

Variables	Univariate analysis		Multivariate analysis
Variables	OR (95% CI)	P value	Adjusted OR (95% CI)	P value
Age	1.01 (0.97–1.06)	0.572	1.00 (0.95–1.06)	0.939
Male sex	3.20 (1.06–9.67)	0.039	3.87 (1.09–13.67)	0.037
Body mass index	0.88 (0.74–1.06)	0.173
Alb	0.47 (0.16–1.37)	0.165
MLR ≥ 0.17	4.71 (1.92–11.52)	<0.001	5.03 (1.92–13.18)	0.001
The location of the lesion in M + L, or U + M + L	2.08 (0.91–4.79)	0.084	3.02 (1.15–7.94)	0.025

OR, Odds ratio; CI, confidence interval; MLR, Monocyte to lymphocyte ratio; U, Upper lobes; M, Middle lobes; L, Lower lobes. The age, sex, and the variables with a P value of less than 0.1 in the univariate analysis were entered into the multivariate logistic regression analysis. Bold indicates significance (P < 0.1 in the univariate analysis and P < 0.05 in the multivariate analysis)

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