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Table 1 Baseline characteristics of the study population

From: Analysis of white-light imaging-based features predictive for determination of lesion depths of superficial flat esophageal squamous cell carcinoma: a retrospective multicenter study from China

Variables

Cohort

Derivation (n = 1146)

Validation (n = 142)

Gender, n (%)

 Male

771 (67.3)

104 (73.2)

 Female

375 (32.7)

38(26.8)

 Lesion numbers, n

1247

149

 Age, years, mean(range)

66 (38–89)

67 (47–82)

 Lesion location, n (%)

 Ut

109 (8.7)

6 (4.0)

 Mt

804 (64.5)

125 (83.9)

 Lt

334 (26.8)

18 (12.1)

 Lesion length, cm, (mean ± SD)

2.4 ± 1.5

1.9 ± 1.3

  > 2.0 cm, n (%)

464 (37.2)

40 (26.8)

  ≤ 2.0 cm, n (%)

783 (62.8)

109 (73.2)

Macroscopic type, n (%)

 0-IIb

964 (77.3)

116 (77.9)

 0-IIa/0-IIc

50 (4.0)

5 (3.4)

 Mixed type

233 (18.7)

28 (18.8)

 0-IIa + IIc

28 (2.2)

5 (3.4)

 0-IIb + IIc

69 (5.5)

7 (4.7)

 0-IIb + IIa

82 (6.6)

11 (7.4)

 0-IIa + IIb

50 (4.0)

3 (2.0)

 0-IIc + IIb

4 (0.3)

2 (1.3)

Surface characteristic, n (%)

 White coating

325 (26.1)

46 (30.9)

 Spontaneous bleeding

38 (3.0)

1 (0.7)

 Granular change

347(27.8)

53(35.6)

 Nodularity

79 (6.3)

10(6.7)

Circumferential extension, n (%)

  ≤ 1/4

651 (52.2)

110 (73.8)

 1/4–1/2

288 (23.1)

12 (8.1)

 1/2–3/4

237 (19.0)

21 (14.1)

  > 3/4

71 (5.7)

6 (4.0)

Depth of invasion, n (%)

 T1a-EP/T1a-LPM

1010 (81.0)

129 (86.6)

 T1a-MM/T1b-SM1

178 (14.3)

16 (10.7)

  ≥ T1b-SM2

59 (4.7)

4 (2.7)

  1. Ut Upper thoracic esophagus, from the sternal notch to the tracheal bifurcation, Mt Middle thoracic esophagus, the proximal half of the two equal portions between the tracheal bifurcation and the esophagogastric junction, Lt lower thoracic esophagus. T1a-EP/LPM lesions confined to the epithelium or amina propria, T1a-MM/T1b-SM1 lesions invade to the muscularis mucosa or slight invasion into the submucosa, T1b-SM2 lesions with deep invasion into the deep submucosa. 0-IIa slightly elevated type, 0-IIb flat type, 0-IIc slightly depressed type