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Table 3 Univariate and multivariate analyses for invasion depths of superficial esophageal squamous cell lesions

From: Analysis of white-light imaging-based features predictive for determination of lesion depths of superficial flat esophageal squamous cell carcinoma: a retrospective multicenter study from China

Variables

Univariate analysis

Multivariate analysis

OR (95%CI)

p value

OR (95%CI)

p value

Gender

1.001 (0.739–1.353)

0.999

NS

 

Age

1.023 (1.004–1.042)

0.018

1.017 (0.996–1.039)

0.105

Lesion location

  

NS

 

 Ut

1.141 (0.684–1.902)

0.613

  

 Mt

0.789 (0.574–1.084)

0.144

  

 Lt

Ref

  

 Length > 2.0 cm

3.025 (2.266–4.039)

 < 0.001

1.898 (1.343–2.686)

 < 0.001

Macroscopic type

  

NS

 

 0-IIa/0-IIc

5.842 (4.255–8.020)

 < 0.001

5.948 (3.168–11.167)

 < 0.001

 Mixed type

4.491 (2.477–8.142)

 < 0.001

4.158 (2.965–5.824)

 < 0.001

 0-IIb

Ref

Ref

 White coating

1.320 (0.969–1.799)

0.078

  

 Spontaneous bleeding

4.272 (2.289–7.980)

 < 0.001

3.732 (1.927–7.236)

 < 0.001

 Granularity

2.234 (1.665–2.995)

 < 0.001

1.548 (1.111–2.155)

 < 0.001

 Nodularity

5.529 (3.540–8.637)

 < 0.001

2.542 (1.550–4.170)

 < 0.001

Circumferential extension

  > 3/4

5.930 (3.530–10.115)

 < 0.001

3.047 (1.692–5.490)

 < 0.001

 1/2–3/4

3.564 (2.474–5.135)

 < 0.001

1.956 (1.275–2.998)

0.002

 1/4–1/2

2.125 (1.465–3.083)

 < 0.001

1.513 (1.003–2.282)

0.048

  ≤ 1/4

Ref

Ref

  1. Ut Upper thoracic esophagus, from the sternal notch to the tracheal bifurcation, Mt Middle thoracic esophagus, the proximal half of the two equal portions between the tracheal bifurcation and the esophagogastric junction, Lt lower thoracic esophagus. 0-IIa slightly elevated type, 0-IIb flat type, 0-IIc slightly depressed type, NS non-sense, and this analysis was not performed